慢性阻塞性肺疾病合并呼吸衰竭呼吸内科治疗效果研究

Effect of Respiratory Medical Treatment on Chronic Obstructive Pulmonary Disease with Respiratory Failure

目的探讨慢性阻塞性肺疾病合并呼吸衰竭呼吸内科治疗效果。方法便利选取符合该院入组条件病例72例,于2018年1月—2019年6月在该院就诊的慢性阻塞性肺疾病合并呼吸衰竭患者。按计算机单盲分组法分为对照组(n=36,常规治疗)及观察组(n=36,常规治疗+无创呼吸机),对比两组血气分析、呼吸频率指标。结果观察组治疗后呼吸频率、心率分别为(24.82±2.59)次/min、(91.15±8.43)次/min,均低于对照组的(27.24±2.61)次/min、(105.27±9.35)次/min,差异有统计学意义(t=3.949、6.730,P=0.000、0.000)。观察组患者住院时间(10.53±2.46)d,对照组患者住院时间(14.86±2.51)d,差异有统计学意义(t=7.392,P=0.000)。观察组治疗后血气分析改善程度高于对照组,血清炎性因子低于对照组(P<0.05)。结论慢性阻塞性肺疾病合并呼吸衰竭呼吸内科治疗时,予以常规治疗联合无创呼吸机,改善血气分析。

Objective To investigate the effect of respiratory medical treatment for chronic obstructive pulmonary disease with respiratory failure.Methods A total of 72 patients with chronic obstructive pulmonary disease and respiratory failure who were admitted to the hospital from January 2018 to June 2019 were conveniently selected.According to the computer single-blind grouping method,they were divided into the control group(n=36),conventional treatment)and the observation group(n=36),conventional treatment+non-invasive ventilator).The two groups were compared for blood gas analysis and respiratory frequency indicators.Results The respiratory rate and heart rate of the observation group after treatment were(24.82±2.59)times/min,(91.15±8.43)times/min,which were lower than those of the control group(27.24±2.61)times/min,(105.27±9.35)times/min,and the differences were statistically significant(t=3.949,6.730,P=0.000,0.000).The length of stay in the observation group was(10.53±2.46)d,and the length of stay in the control group was(14.86±2.51)d.The difference was statistically significant(t=7.392,P=0.000).The improvement of blood gas analysis in the observation group was higher than that in the control group,and serum inflammatory factors were lower than those in the control group(P<0.05).Conclusion In the treatment of chronic obstructive pulmonary disease and respiratory failure with respiratory medicine,conventional therapy combined with non-invasive ventilator can improve blood gas analysis.