磷酸肌酸钠治疗心肌炎的效果分析

Effect of Creatine Phosphate on Myocarditis

目的对心肌炎患儿实施磷酸肌酸钠治疗的临床效果进行分析和研究。方法方便选择该院收治的儿童病毒性心肌炎患儿80例作为该次研究纳入的研究对象,选取时间段为为2018年1月—2019年4月。按照硬币法将这些患儿划分为果糖二磷酸钠组和磷酸肌酸钠组,每组40例,采用果糖二磷酸钠对果糖二磷酸钠组进行治疗,采用磷酸肌酸钠对磷酸肌酸钠组进行治疗,对两组患儿的治疗效果进行分析和比较。结果在经过精心的治疗之后,果糖二磷酸钠组的cTnT指标为(2.7±1.3)U/L,LDH指标为(75.1±4.7)U/L,CK-MB指标为(24.1±3.3)U/L,CK指标为(173.3±27.5)U/L,磷酸肌酸钠组的cTnT指标为(1.2±1.3)U/L,LDH指标为(53.8±3.7)U/L,CK-MB指标为(15.5±3.1)U/L,CK指标为(131.8±25.4)U/L。磷酸肌酸钠组在生化指标方面均明显优于果糖二磷酸钠组,两组比较差异有统计学意义(t=2.355、3.728、3.154、10.295,P<0.05)。磷酸肌酸钠组(95.0%)明显优于果糖二磷酸钠组总有效率(80.0%),两组比较经过统计学检验显示,差异有统计学意义(χ2=15.723,P<0.05)。磷酸肌酸钠组在不良反应发生率(5.0%)方面明显优于果糖二磷酸钠组不良反应发生率(17.5%),两组比较经过统计学检验显示,差异有统计学意义(χ2=6.472,P<0.05)。结论采用磷酸肌酸钠对病毒性心肌炎患者进行治疗具有十分确切的效果,可以有效地改善患者的各项指标,而且具有很高的安全性,属于一种有效的治疗方法。

Objective To analyze and study the clinical effect of creatine phosphate treatment in children with myocarditis.Methods Convenient selection eighty children with viral myocarditis treated in the hospital were selected as the research subjects included in this study.The time period was from January 2018 to April 2019.These children were divided into the fructose sodium diphosphate group and the sodium creatine phosphate group according to the coin method,with 40 patients in each group.The sodium group was treated,and the treatment effects of the two groups of children were analyzed and compared.Results After careful treatment,the cTnT index of the fructose sodium diphosphate group was(2.7±1.3)U/L,the LDH index was(75.1±4.7)U/L,and the CK-MB index was(24.1±3.3)U/L,CK index was(173.3±27.5)U/L,cTnT index of creatine sodium phosphate group was(1.2±1.3)U/L,and LDH index was(53.8±3.7)U/L,CK-MB index was(15.5±3.1)U/L,CK index was(131.8±25.4)U/L.Biochemical indicators of the creatine sodium phosphate group were significantly better than those of the sodium fructose diphosphate group,and the comparison between the two groups showed statistical tests(t=2.355,3.728,3.154,10.295,P<0.05).The total effective rate of the sodium creatine phosphate group(95.0%)was significantly better than that of the sodium fructose diphosphate group(80.0%),and the comparison between the two groups was shown by statistical tests(χ2=15.723,P<0.05).The incidence of adverse reactions(5.0%)in the creatine sodium phosphate group was significantly better than that in the sodium fructose diphosphate group(17.5%),and the comparison between the two groups showed statistically(χ2=6.472,P<0.05).Conclusion The use of creatine phosphate in the treatment of patients with viral myocarditis has a very precise effect,can effectively improve the patient's various indicators,and has high safety,which is an effective treatment method.