食管-胃结合部腺癌手术治疗的共识与争议

Consensus and controversy regarding the treatment of adenocarcinoma of the esophagogastric junction

食管-胃结合部腺癌(adenocarcinoma of esophagogastric junction,AEG)在全球的发病率不断升高,因其特殊的解剖位置、独特的生物学行为被越来越多的临床工作者所重视。目前国内外虽然对AEG的发病、分型等已形成了一定共识,但在更多方面,尤其是外科治疗手段,诸如手术路径、胃的切除范围、淋巴结的清扫范围、消化道重建等方面仍存在较多争议。这些争议不仅限制了对AEG治疗的探索与发展,同时使得对AEG的规范化诊疗变得更加困难。本文结合近些年的相关文献,就目前AEG治疗的国内外相关共识与争议进行综述,以期为临床诊治提供更加合理、有效的方法。

The incidence of adenocarcinoma of the esophagogastric junction(AEG)has been increasing worldwide,which attracts great attention among medical professionals because of its anatomical location and unique biological behavior.Although some consensus has been reached regarding the pathogenesis and classification of AEG,there remain debates about its surgical treatment,including the surgical route,scope of gastrectomy,range of lymph node dissection,and digestive tract reconstruction.These debates limit the exploration and development of AEG treatment and make it difficult to standardize the diagnosis and treatment of AEG.This study reviews the relevant literature on AEG in recent years and comprehensively discusses the current consensus and controversy regarding the treatment of AEG with the aim to provide a more reasonable and effective method for its clinical diagnosis and treatment.