布托啡诺复合地佐辛超前镇痛对胫腓骨骨折患者术后镇静及恢复的影响

Effect of Butorphanol Tartrate Combined with Dizosin on the Postoperative Sedation and Recovery of Patients with Tibiofibular Fracture

目的观察布托啡诺复合地佐辛超前镇痛对胫腓骨骨折患者术后镇静及恢复的影响。方法选取2017年7月-2019年7月天津市西青医院收治的102例胫腓骨骨折患者,随机数字表法分为观察组与对照组,每组各51例。对照组予以微量泵注布托啡诺,观察组在对照组基础上复合地佐辛进行超前镇痛。比较两组患者术后不同时间点的疼痛程度[视觉模拟评分法(VAS)]及镇静评分(Ramsay镇静评分),记录其术后24 h内的不良反应发生情况。结果观察组患者术后4、8、12 h VAS评分均明显低于对照组(P<0.05);观察组患者术后4、8、12 h Ramsay评分均明显高于对照组(P<0.05)。结论对胫腓骨骨折患者实施布托啡诺复合地佐辛超前镇痛可明显改善其术后疼痛,镇静效果好,且不良反应少,安全性高。

Objective To investigate the effect of Butorphanol Tartrate combined with Dizosin on postoperative sedation and recovery of patients with tibiofibular fracture.Methods 102 patients with tibiofibular fracture who were treated in our hospital from July 2017 to July 2019 were selected as subjects,and randomly divided into the observation group and the control group with 51 cases each.The control group was injected with Butorphanol Tartrate by micro pump,and the observation group was given advanced analgesia with Dizosin.The pain degree(VAS)and sedation score(Ramsay Sedation score)at different time points were compared between the two groups,and the adverse reactions within 24 hours after operation were recorded.Results The VAS score of the observation group was significantly lower than that of the control group at 4 h,8 h and 12 h after operation(P<0.05);the Ramsay score of the observation group was significantly higher than that of the control group at 4 h,8 h and 12 h after operation(P<0.05).Conclusion Butorphanol Tartrate combined with Dizosin can significantly improve the postoperative pain,and has good sedative effect,less adverse reactions and high safety.