瑞芬太尼复合异丙酚应用于脊柱结核患者麻醉苏醒期的效果探讨

Effect of remifentanil combined with propofol on anesthesia recovery period in patients with spinal tuberculosis

目的探讨瑞芬太尼复合异丙酚应用于脊柱结核患者麻醉苏醒期的效果。选择2016年10月~2018年10月治疗的脊柱结核患者80例作为对象,分为对照组(n=40)和观察组(n=40)。对照组予芬太尼联合异丙酚治疗,观察组予瑞芬太尼联合异丙酚治疗,治疗后对两组患者的麻醉效果进行评估,比较两组的睁眼时间、睫毛反射消失时间、针刺反应消失时间、血氧饱和度、心率、呼吸及苏醒时间和拔管时间。结果观察组患者的苏醒时间和拔管时间明显短于对照组(P<0.05);观察组的血氧饱和度明显高于对照组(P<0.05)。观察组与对照组麻醉过程中的恶心呕吐、低血压、躁动、呼吸抑制及心动过缓发生率比较,差异均无统计学意义(P>0.05);麻醉前后对照组和观察组的心率和呼吸水平比较,差异有统计学意义(P<0.05)。结论将瑞芬太尼复合异丙酚用于治疗脊柱结核患者麻醉苏醒期效果好,对患者术后提高患者的恢复意识有积极作用,有效降低了患者的不良发生率,值得推广应用。

Objective To investigate the effect of remifentanil combined with propofol on anesthesia recovery in patients with spinal tuberculosis.Methods Eighty patients with spinal tuberculosis treated from October 2016 to October 2018 were selected and divided into control group(n=40)and observation group(n=40).The control group was treated with fentanyl and propofol.The observation group was treated with remifentanil combined with propofol.The effect of the patients was evaluated after treatment.The blink time,disappearance time of the eyelash reflex and disappearance time of the acupuncture reaction,blood oxygen saturation,heart rate,breathing,and recovery time and extubation time were compared between the two groups.Results The recovery time and extubation time of the patients in the observation group were significantly shorter than those in the control group(P<0.05);The blood oxygen saturation of the observation group was significantly higher than that of the control group(P<0.05).There was no significant difference in the incidence of nausea and vomiting,hypotension,agitation,respiratory depression and bradycardia during the anesthesia between the observation group and the control group(P>0.05).There was significant difference in heart rate and breathing between the control group and the observation group(P<0.05).Conclusion Remifentanil combined with propofol is effective in treating anesthesia recovery in patients with spinal tuberculosis.It has a positive effect on patients'recovery consciousness after surgery,and effectively reduces the incidence of adverse reactions.It is worthy of popularization and application.