不同分子质量辛烯基琥珀酸蜡质玉米淀粉酯对柚皮素的增溶作用研究

Solubilization of Naringenin by Octenyl Succinic Acid Esterified Waxy Corn Starch with Different Molecular Weights

为了探究辛烯基琥珀酸淀粉酯作为柑橘类黄酮增溶剂的潜力,以蜡质玉米淀粉为原料制备辛烯基琥珀酸蜡质玉米淀粉酯(OSAS),以柚皮素(NAR)为对象构建NAR-OSAS饱和水体系,探讨了不同分子质量OSAS对NAR增溶效果的影响及其相互作用。结果表明:在采用不同分子质量OSAS包合NAR得到的5种聚集体中,NAR含量随OSAS分子质量的减小先增加后降低。NAR含量最高的NAR与中分子质量OSAS聚集体(NAR-M-OSAS)样品,其水体系相溶解度曲线符合Higuchi分类法中AL型,NAR溶解度可提高达1023倍。另外,NAR进入M-OSAS腔体且包合在分子空腔中,得到的NAR-M-OSAS聚集体颗粒粒径为222.53 nm,且粒径在10~1000 nm范围内分布均匀,形成分散的聚集体溶液。研究结果为辛烯基琥珀酸改性淀粉酯的更广泛应用提供依据,为柑橘类黄酮的增溶设计提供新的理论基础。

To explore the potentials of octenyl succinic acid esterified starch as a solubilizer for citrus flavonoids,waxy corn starch was used as a raw material to prepare octenyl succinic acid esterified starches (OSAS),and their saturated water system with naringenin (NAR) was constructed.Effects of different molecular weights of OSAS on the solubilization of NAR and their interactions were investigated.The results showed that in the five aggregates formed by NAR and OSAS with different molecular weights,the NAR content was initially increased but eventually decreased with further reduction of OSAS molecular weights.The NAR-M-OSAS sample with the highest NAR content had a water system phase solubility curve that conformed to the AL type in Higuchi classification,and the NAR solubility could be increased by 1023 times.In addition,the NAR entered into the cavity of M-OSAS and inserted into the molecular cavity.A dispersed solution was formed by NAR-M-OSAS aggregate with 222.53 nm in particle size and 10~1000 nm in uniformly distributed range.All the results provided a basis for the wider application of octenyl succinic acid modified starch ester,and provided a new theoretical basis for the solubilization design of citrus flavonoids.