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丹栀桑芩汤治疗肝肺郁热型经前痤疮的疗效观察

Clinical observation of Danzhi Sangqin decoction in the treatment of premenstrual acne with liver and lung stagnation
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摘要 目的观察丹栀桑芩汤治疗肝肺郁热型经前痤疮的临床疗效。方法选取绍兴市中心医院皮肤科2016年7月至2018年11月诊治的肝肺郁热型经前痤疮患者60例为研究对象,采用随机数字表法分为对照组(n=28)和治疗组(n=32)。治疗组以自拟丹栀桑芩汤治疗,对照组口服异维A酸胶囊和维生素B6治疗,两组治疗4周为1个疗程。比较两组临床疗效及不良反应发生率。结果治疗组显效18例,有效11例,无效3例,总有效率为90.6%(29/32);对照组显效16例,有效10例,无效2例,总有效率为92.9%(26/28),两组总有效率差异无统计学意义(P>0.05);治疗组不良反应发生率为3.1%(1/32),显著低于对照组的21.4%(6/28),差异有统计学意义(χ2=6.281,P<0.05)。结论丹栀桑芩汤治疗肝肺郁热型经前痤疮的临床疗效与异维A酸胶囊相近,但不良反应发生率低。 Objective To observe the clinical efficacy of Danzhi Sangqin decoction in the treatment of premenstrual acne with liver and lung stagnation.Methods Sixty patients with liver and lung stagnation premenstrual acne diagnosed and treated in the Department of Dermatology of Shaoxing Central Hospital from July 2016 to November 2018 were selected in the research.They were divided into the control group(n=28)and treatment group(n=32)by random number table method.The treatment group was treated with self-made Danzhi Sangqin decoction,and the control group was orally treated with isotretinoin capsules and vitamin B6.The two groups were treated for 1 week.The clinical efficacy and the incidence of adverse reactions were compared between the two groups.Results In the treatment group,18 cases were markedly effective,11 cases were effective,and 3 cases were ineffective,and the total effective rate was 90.6%(29/32).In the control group,16 cases were significantly effective,10 cases were effective,and 2 cases were ineffective,and the total effective rate was 92.9%(26/28).There was no statistically significant difference in the total effective rate between the two groups(P>0.05).The incidence of adverse reactions in the treatment group was 3.1%(1/32),which was significantly lower than that in the control group[21.4%(6/28)],the difference was statistically significant(χ2=6.281,P<0.05).Conclusion The clinical efficacy of Danzhi Sangqin decoction in the treatment of premenstrual acne with liver and lung stagnation is similar to that of isotretinoin capsules,but the incidence of adverse reactions is low.
作者 王卫兰 朱晓亮 刘姣 江松平 Wang Weilan;Zhu Xiaoliang;Liu Jiao;Jiang Songping(Department of Dermatology,Shaoxing Central Hospital,Shaoxing,Zhejiang 312030,China;Department of Traditional Chinese Medicine,the Traditional Chinese Medicine Hospital of Qingtian County,Zhejiang 323900,China;Department of Traditional Chinese Medicine,the Maternal and Child Health Hospital of Lishui,Lishui,Zhejiang 323000,China)
出处 《中国基层医药》 CAS 2020年第8期966-969,共4页 Chinese Journal of Primary Medicine and Pharmacy
基金 浙江省中医药科技计划项目(2014ZB139)。
关键词 痤疮 红斑 卵泡期 月经 肝肺郁热型 丹栀桑芩汤 异维A酸胶囊 医学 中国传统 疗效比较研究 Rosacea Follicular phase Menstruation Heat stagnation of liver and lung Danzhi sangzhi decoction Isotretinoin capsule Medicine chinese traditional Comparative effectiveness research
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