手性碳量子点的制备及其应用

Synthesis and Applications of Chiral Carbon Quantum Dots

手性碳量子点(CQDs)因兼具优异的荧光性质、良好的生物相容性、较低的毒性、易于功能化以及手性特征等,在催化、检测和生物医学等领域具有广阔的应用潜力。目前,通过一步法或两步法制备的手性CQDs,已应用于手性催化、手性检测、高尔基体靶向成像、选择性调控酶和蛋白活性、选择性调控细胞能量代谢和促进植物生长等领域。然而,手性CQDs的发展初露头角,需进一步完善可控合成工艺,制备高荧光量子产率的长波长手性CQDs,使其在生物医学等领域绽放异彩。

Chiral carbon quantum dots(CQDs)have wide application potential in catalysis,detection and biomedicine owing to their excellent fluorescence properties,good biocompatibility,low toxicity,easy functionalization and chiral characteristics.At present,chiral CQDs are synthesized by one-step or two-step methods,and applied to chiral catalysis,chiral detection,Golgi apparatus targeted imaging,selective tuning of enzyme and protein activity,selective regulation of cellular energy metabolism,promotion of plant growth,etc.However,the development of chiral CQDs is just beginning.It is necessary to further improve the controllable synthesis process and prepare long wavelength chiral CQDs with high fluorescence quantum yield,so as to make them shine brilliantly in biomedical and other fields.