他汀类药物在临床用药中的安全性

The Safety of Statins in Clinical Medicine

他汀类药物是临床心血管疾病治疗一线用药,属于临床一类广泛使用的口服降脂药物。目前,随着临床应用指南的不断更新,在治疗代谢性疾病、脑血管疾病、心血管疾病中均有应用。任何药物都存在潜在的毒性和不良反应,并且可能随着剂量增加治疗疗程的延长而增加。因此,研究他汀类药物在临床用药中的安全性具有重要的意义。本文对他汀类药物在临床用药中的安全性进行综述,以期为临床合理用药提供一定的参考。

Statins are the first-line drugs for the treatment of clinical cardiovascular diseases and belong to the clinically widely used oral lipid-lowering drugs.At present,with the continuous update of clinical application guidelines,it has been used in the treatment of metabolic diseases,cerebrovascular diseases and cardiovascular diseases.Any drug has potential toxicity and adverse reactions,and may increase as the dose increases and the course of treatment increases.Therefore,it is of great significance to study the safety of statins in clinical medicine.This article reviews the safety of statins in clinical medicine,in order to provide a certain reference for clinical rational medicine.