应用穴位贴敷治疗肾虚痰湿型多囊卵巢综合征的疗效观察

Observation on the therapeutic effect of acupoint application on polycystic ovary syndrome with kidney deficiency and phlegm dampness type

目的探讨穴位贴敷联合中药治疗肾虚痰湿型多囊卵巢综合征的临床疗效。方法选取2019年1~6月于我院门诊就诊的60例肾虚痰湿型多囊卵巢综合征患者,随机分为三组,观察组(多囊I号方合穴位贴敷)、对照组1(多囊I号方合达英-35)、对照组2(达英-35)进行3个月经周期的治疗,观察并统计患者的临床疗效、中医证候积分、血清性激素水平[黄体生成素(LH)、卵泡刺激素(FSH)、睾酮(T)]、抗苗勒氏管激素(AMH)及月经周期改善情况。结果经过治疗后观察组总有效率为90.0%,高于对照组1的73.7%和对照组2的55.0%,差异有统计学意义(P<0.05)。经治疗后三组性激素水平、AMH均低于治疗前,与治疗前比较,差异有统计学意义(P<0.05)。观察组治疗后性激素水平、AMH低于对照组1和对照组2,差异有统计学意义(P<0.05)。经治疗后,三组月经天数短于治疗前,症候评分低于治疗前,与治疗前比较,差异有统计学意义(P<0.05)。治疗后观察组月经天数短于对照组1、对照组2,症候评分低于对照组1、对照组2,差异有统计学意义(P<0.05)。结论穴位贴敷联合补肾化痰中药治疗肾虚痰湿型多囊卵巢综合征可改善月经周期及女性内分泌水平,促进卵泡发育,提高排卵率,疗效显著且无不良反应。

Objective To explore the clinical efficacy of acupoint application combined with traditional Chinese medicine in the treatment of polycystic ovary syndrome with kidney deficiency and phlegm dampness type.Methods Sixty polycystic ovary syndrome patients with kidney deficiency and phlegm-dampness type who were treated in our outpatient clinic from January to June 2019 were randomly divided into three groups including the observation group(polycystic recipe I combined with acupoint application),control group 1(polycystic recipe I Daying-35)and control group 2(Daying-35).They were treated for three menstrual cycles.The clinical efficacy of patients,TCM syndrome scores,and serum sex hormone levels[Luteinizing hormone(LH),follicle stimulating hormone(FSH),testosterone(T)],anti-Mullerian hormone(AMH)and improvement of menstrual cycle were observed and counted.Results After treatment,the total effective rate in the observation group was 90.0%,which was higher than 73.7%in the control group 1 and 55.0%in the control group 2(P<0.05).After treatment,the levels of sex hormones and AMH in the three groups were lower than those before treatment,and there was a statistically significant difference(P<0.05).After treatment,the levels of sex hormones and AMH in the observation group were lower than those in the control group 1 and the control group 2(P<0.05).After treatment,the menstrual days in the three groups were shorter than those before treatment,and their symptom scores were lower than before treatment,which was statistically significant(P<0.05).The menstrual days in the observation group after treatment were shorter than those in the control group 1,control group 2,and the symptom scores in the observation group were lower than those in the control group 1,control group 2,The difference was statistically significant(P<0.05).Conclusion Acupoint application combined with Bushen Huatan traditional Chinese medicine for treatment of polycystic ovary syndrome with kidney deficiency and phlegm-dampness type can improve menstrual cycle and female endocrine level,promote follicular development and increase ovulation rate.It is effective and has no adverse effects.