升主动脉内球囊反搏术仿真

Simulation of ascending aorta balloon counter pulsation

为了探究在升主动脉耦合球囊反搏泵并在其后加瓣膜的方法对心衰的辅助效果,根据电液比拟,在周身血液循环系统模型的基础上搭建升主动脉耦合球囊反搏泵模型和在球囊反搏泵后加瓣膜模型,根据等效电路图,建立数学方程.用Matlab完成数值模拟,探究2种方法对心衰的辅助效果,发现心衰状态下2种模型均能提高主动脉舒张期压力,减少左心室射血阻力、心室做功,增加每搏输出量和射血分数.结果表明:2种模型对心衰均有辅助效果.对2种方法进行对比分析后发现,在球囊后放置人工瓣膜能防止外周血液在球囊放气时反流,并增强主动脉的抽吸作用,降低了主动脉窦压力,进一步减小了左心室射血阻力和心室做功,表明升主动脉耦合球囊后加瓣膜模型对心衰的辅助效果更好.

To explore the assistant effect of balloon pump coupled with ascending aorta on heart failure,the model of balloon pump coupled with ascending aorta and the model of valve added after balloon pump were established on the basis of systemic blood circulation system model by electro-hydraulic analogy,and the mathematics equation was established according to the equivalent circuit diagram.Using Matlab to complete numerical simulation and the auxiliary effect of the two methods on heart failure was explored.It is found that both models can increase aortic diastolic pressure,reduce left ventricular ejection resistance and ventricular work,and increase stroke output and ejection fraction.Both models have auxiliary effect on heart failure.By comparing between the two methods,it is found that the artificial valve placed behind the balloon can prevent the peripheral blood from refluxing during the balloon deflation,enhance the suction of aorta,reduce the pressure of aortic sinus,and further reduce the left ventricular ejection resistance and ventricular work.The model of balloon-assisted valvular implantation coupled with ascending aorta is feasible.It has better effect on heart failure.