儿童支气管哮喘急性发作氧驱动雾化吸入治疗的临床观察及疗效评价

Clinical Observation and Efficacy Evaluation of Oxygen Driven Aerosol Inhalation in Treatment of Acute Attack of Bronchial Asthma in Children

目的:评价儿童支气管哮喘急性发作氧驱动雾化吸入治疗的临床疗效。方法:按照随机双盲法将2018年3月-2019年3月在我院就诊的108例儿童支气管哮喘急性发作患儿分为两组,对照组和研究组均54例。给予对照组压缩雾化吸入治疗,给予研究组氧驱动雾化吸入治疗。比较两组临床疗效、肺功能、血氧饱和度以及不良反应情况。结果:研究组治疗总有效率较对照组高,不良反应总发生率较对照组低,差异有统计学意义(P<0.05)。治疗后研究组FEV1、FVC、Sa O2水平较对照组高,差异有统计学意义(P<0.05)。结论:氧驱动雾化吸入治疗儿童支气管哮喘急性发作的疗效确切,可改善肺功能,且较为安全,值得临床推广。

Objective:To evaluate the clinical efficacy of oxygen driven aerosol inhalation in treatment of acute attack of bronchial asthma in children.Methods:Totally 108 children with acute attack of bronchial asthma treated in our hospital from March 2018 to March 2019 were divided into control group and study group by randomized double-blind method,with 54 children in each group.The control group was given compressor aerosol inhalation,while the study group given oxygen driven aerosol inhalation.The clinical efficacy,lung functions,saturations of blood oxygen,and incidences of adverse reactions were compared between the two groups.Results:The study group had a significantly higher overall response rate and a significantly lower overall incidence of adverse reactions than the control group(P<0.05).After treatment,the study group had significantly higher levels of FEV 1,FVC,and SaO 2 than the control group(P<0.05).Conclusion:Oxygen driven aerosol inhalation in treatment of acute attack of bronchial asthma in children has definite efficacy,improves the lung function,and is safe,and consequently holds promise for clinical application.