血小板在脓毒症各器官功能障碍中作用机制的研究进展

Research progress on the mechanism of platelet in the organs dysfunction of sepsis

脓毒症为感染致全身免疫失调的炎症反应综合征,是多脏器受累疾病.血小板在脓毒症中起重要作用,可用于判断脓毒症患者病情严重程度,且血小板减少提示病情危重.血小板可作为免疫系统、凝血系统、内皮细胞、细菌产物间的中心介质.故本文侧重综述血小板在脓毒症各器官功能障碍中的作用机制.

Sepsis is an inflammatory response syndrome with systemic immune disorders caused by infection,and it is a disease involving multiple organs.Platelet plays an important role in sepsis,which can be used to judge the severity degree of sepsis patients,and thrombocytopenia indicates the critical condition.Platelet can be used as central mediators between immune system,coagulation system,endothelial cells and bacterial products.Therefore,this paper focuses on reviewing the mechanism of platelet in the organs dysfunction of sepsis.