摘要
近年来大量临床及基础研究报道,Wnt/p-catenin信号通路与多种神经系统疾病的发生发展有着密切关系。为提高人们对Wnt/p-catenin信号通路与神经系统疾病关系的重视,并为治疗提供新的靶点,本文就Wnt/p-catenin信号通路与阿尔茨海默病、帕金森病、癫痫、多发性硬化症以及重症肌无力关系的研究进展作一综述。
Abundant clinical and basic studies in recent years reported the high association of Wnt/β-catenin signaling pathway with the incidence and development of multiple neurological disorders.In order to improve the attention about the relationship between Wnt/β-catenin signaling pathway and neurological disorders,and to provide new therapy target,this article reviews the research progress on the relationship between wnt/β-catenin signaling pathway and Parkinson′s disease,Alzheimer′s disease,epilepsy,multiple sclerosis and myasthenia gravis.
作者
洪康杰
章正祥
李净娅
蒋旭宏
裘昌林
侯群
裘辉
Hong Kangjie;Zhang Zhengxiang;Li Jingya;Jiang Xuhong;Qiu Changlin;Hou Qun;Qiu Hui(the First Clinical College of Zhejiang Chinese Medical University,Hangzhou 310053,China;Department of Neurology,the First Affiliated Hospital of Zhejiang Chinese Medical University,Hangzhou 310006,China;Department of Traditional Chinese Medicine,the Third Affiliated Hospital of Zhejiang Chinese Medical University,Hangzhou 310005,China)
出处
《中国医师杂志》
CAS
2020年第5期789-793,共5页
Journal of Chinese Physician
基金
2017年度浙江省中医药科学研究基金项目(2017ZA047)
浙江省中医药科技计划项目(2014ZA048,2019ZA064)
2012年全国名老中医药专家传承工作室建设项目(国中医药人教函〔2012〕149号)
国家中医药管理局全国名老中医药专家传承工作室建设项目(国中医药人教发〔2016〕42号)。
