血浆中转录因子21基因启动子甲基化在肺癌早期临床诊断的意义被引量：2

Implication of plasma methylated transcription factor 21 gene promoter in early clinical diagnosis of lung cancer

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摘要转录因子21(TCF-21)基因是近几年开始研究的一个较新的基因,是最近发现的癌症异常启动子高甲基化的一个靶点,在基因组筛查中发现了癌症中DNA高甲基化的区域[1]。本实验采用巢式甲基化特异性聚合酶链反应(nMSP)检测肺癌患者与健康人群血浆TCF-21基因甲基化特异性,探讨TCF-21基因对早期肺癌诊断的意义。

作者杨胜壮梁祥森孙宇刘涛刘文洲冼磊 Yang Shengzhuang;Liang Xiangsen;Sun Yu;Liu Tao;Liu Wenzhou;Xian Lei(Department of Cardiothoracic Surgery,the Second Affiliated Hospital,Guangxi Medical University,Nanning 530007,China)

机构地区广西医科大学第二附属医院心胸外科

出处《中华实验外科杂志》 CAS CSCD 北大核心 2020年第1期177-177,共1页 Chinese Journal of Experimental Surgery

基金广西医疗卫生适宜技术开发与推广应用项目(S2017011)。

关键词早期临床诊断高甲基化基因启动子甲基化早期肺癌诊断甲基化特异性健康人群 TCF 癌症

分类号 R73 [医药卫生—肿瘤]

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参考文献1

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