孤立性三尖瓣反流的治疗研究进展

Research progress on the treatment of isolated tricuspid regurgitation

孤立性三尖瓣反流是指不合并左心瓣膜病变及肺动脉高压情况下单独出现的三尖瓣反流病变。随着心房颤动(房颤)发病率的上升及心内起搏器的使用增加,该疾病发病率逐年上升,若进展至重度将严重影响患者的生存率及生活质量。外科手术作为目前主要治疗手段,受限于较高的围术期死亡率而较少开展。介入治疗方兴未艾,有效性及安全性尚未得到验证。本文尝试对孤立性三尖瓣反流的病因、自然病程及不良后果、当前的治疗策略、手术指征、术式选择、疗效评价、手术预后影响因素及介入治疗进展等进行综述,以期为广大心血管病医师提供参考,并为进一步研究提供思路。

With the prevalence of atrial fibrillation and the increasing use of intracardiac pacemakers,the incidence of isolated tricuspid regurgitation is gradually increasing.Severe isolated tricuspid regurgitation has a seriously negative effect on the survival rate and life quality of patients.As the major invasive therapy,surgery is not routinely carried out due to high perioperative mortality.This article attempts to summarize the etiology,natural course and adverse consequences of isolated tricuspid regurgitation,current treatment strategies,surgical indications and techniques,efficacy evaluation,prognostic factors and transcatheter treatment progress of isolated tricuspid regurgitation,aiming to provide references for cardiologists and further researches.