女性生殖道沙眼衣原体感染与阴道分泌物检测结果的相关性分析

Correlation analysis of Chlamydia trachomatis infection in female genital tract and the detection results of vaginal secretions

目的探讨女性生殖道沙眼衣原体(Chlamydia trachomatis,CT)感染与阴道分泌物检测结果的相关性。方法采用聚合酶链反应(PCR)法检测CT,通过镜检法检测阴道分泌物白细胞(WBC)计数、真菌、滴虫,采用细菌性阴道病联合检测试剂盒检测过氧化氢(H2O2)、唾液酸苷酶(SNa)、白细胞酯酶(LE)水平。结果CT总的阳性率为11.40%,而≤25岁患者中CT阳性率为15.91%;CT阳性患者阴道分泌物中WBC计数、LE的阳性率分别为46.81%和50.35%;CT阴性患者阴道分泌物中WBC计数、LE的阳性率分别为29.65%和41.42%,差异有统计学意义(P<0.05)。结论CT是女性生殖道感染的重要病原体,≤25岁患者阳性率最高。CT与阴道分泌物WBC计数、LE活性呈正相关。

Objective To investigate the correlation of Chlamydia trachomatis(CT)infection in female genital tract and the detection results of vaginal secretions.Methods CT was detected by PCR;the count of leukocyte(WBC),fungi and trichomonas in vaginal secretions were detected by microscopic examination,and hydrogen peroxide(H2 O2),sialidase(SNa)and leukocyte esterase(LE)were detected by the joint detection kit of bacterial vaginosis.Results The total positive rate of CT was 11.40%,and the positive rate of CT in patients under 25 years old was 15.91%.The positive rate of WBC and LE in the vaginal secretions of CT positive patients were 46.81%and 50.35%respectively,and the positive rates of WBC and LE in the vaginal secretions of CT negative patients were 29.65%and 41.42%respectively,and the difference was statistically significant(P<0.05).Conlusions CT is an important pathogen of female genital tract infection,the highest detection rate is in patients under 25 years old.CT infection is positively correlated with WBC count and LE activity of vaginal secretions.