原发性系统性淀粉样变病一例

A case of primary systemic amyloidosis

49岁男性患者,胸背部皮损1年余。皮肤科情况:颈部、胸部、背部、双前臂可见片状红斑、瘀点、瘀斑,伴轻度糜烂。组织病理:真皮内可见团块状淀粉样物质沉积,部分围绕在毛囊及血管周围。刚果红染色阳性。骨髓穿刺:多发性骨髓瘤。诊断:原发性系统性淀粉样变病。

A 49-year-old man presented with rash on the chest and back for 1 year.Physical examination showed erythema and petechiae on his two-forearm,chest and back with slight erosion.Histological findings showed that clumps of amyloid existed in the dermis surrounding the hair follicles and blood vessels,additionally,Congo red staining was positive.Bone marrow puncture indicated multiple myeloma,and primary systemic amyloidosis was regarded as final diagnosis.