我国口咽癌与HPV的关系

Relationship between HPV and oropharyngeal cancer in China

口咽癌是常见的头颈部恶性肿瘤之一,据流行病学研究显示,我国口咽癌发病率及死亡率正逐年上升。除烟酒外,人乳头瘤病毒(HPV)现已被证实是口咽癌病因之一,我国学者也证实了我国口咽癌与HPV的相关性,但HPV感染在我国口咽癌患者中的占比仍需更大样本的数据统计。目前,国内外研究都表明HPV相关性口咽癌患者的疗效及预后均较好,该类患者的治疗模式为目前研究热点。另外,HPV疫苗、人群口咽/口腔部位HPV感染的筛查为该类疾病的预防提供了进一步的研究方向。

Oropharyngeal cancer(OPC)is one of the head and neck cancers.According to epidemiological data,the incidence and mortality of OPC in China are increasing.In addition to tobacco and alcohol,human papillomavirus(HPV)has been proved to be one of the causes of OPC.Chinese scholars have also confirmed the correlation between HPV and OPC in China,but the proportion of HPV infection in OPC in China still needs a larger sample.Because lots of studies have shown that the efficacy and prognosis of HPV-related OPC are better,the treatment of this type of patients is the current research hotspot.Meanwhile,HPV vaccine and the screening method for HPV infection in the oropharynx or oral cavity of the population deserve further research.