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注射用奥美拉唑钠与兰索拉唑治疗消化性溃疡出血的效果比较 被引量:7

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摘要 目的比较注射用奥美拉唑钠与兰索拉唑治疗消化性溃疡出血的临床效果。方法选取2016年1月-2019年4月东莞市樟木头医院收治的消化性溃疡出血患者40例,采用随机数字表法分为A组和B组,每组20例。在常规治疗基础上,A组给予注射用奥美拉唑钠静脉滴注治疗,B组给予注射用兰索拉唑静脉滴注治疗。比较2组大便潜血停止时间,治疗前后心率、血压、血红蛋白(Hb)、红细胞计数(RBC)、C-反应蛋白(CRP)及尿素氮(BUN)水平。结果B组大便潜血停止时间为(3.9±0.8)d,短于A组的(5.4±1.2)d(t=4.651,P<0.01);治疗后,2组收缩压、舒张压、Hb、RBC水平均较治疗前升高,心率、CRP、BUN水平均较治疗前降低,且B组升高或降低幅度大于A组(P<0.05或P<0.01)。结论相较于注射用奥美拉唑钠,注射用兰索拉唑在消化性溃疡出血患者的治疗中更有利于迅速止血、平稳生命体征、促进血液循环、改善应激状态,临床应用价值更高,值得推广应用。
出处 《临床合理用药杂志》 2020年第14期57-58,共2页 Chinese Journal of Clinical Rational Drug Use
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