摘要
目的总结血管周上皮样细胞肿瘤(PEComas)的诊断与治疗,以减少临床误诊、漏诊及误治的发生。方法分析1例转录因子E3(TFE3)基因重排输尿管部PEComas的临床资料、组织学形态、免疫组织化学染色及基因检测结果,并复习相关文献。结果诊断该院1例输尿管部PEComas患者,术后建议密切随访。目前患者病情平稳,无复发和转移。结论对于无法明确诊断的泌尿系统疾病,需及时进行病理明确诊断。针对PEComas研究数据的积累,以及包括遗传背景在内的相关研究,有助于确定罕见病例的起源、治疗方案及预后。
Objective To summarize the diagnosis and treatment of perivascular epithelioid cell neoplasm(PEComas),so as to reduce the clinical misdiagnosis,missed diagnosis and mistreatment.Methods The clinical data,histology,immunohistochemical staining and genetic testing of 1 case of ureteral PEComas with transcription factor E3(TFE3)gene rearrangement were reported and analyzed,and the related literatures were reviewed.Results A patient with ureteral PEComas was diagnosed in this hospital,and close following-up was recommended after surgery.Currently,the condition of the patient is stable without recurrence and metastasis.Conclusion For urinary system diseases that cannot be clearly diagnosed,it is necessary to get a pathological diagnosis in time.The accumulation of research data for PEComas,and exploration including genetic background can help to identify the origin,therapeutic regimen and prognosis of rare cases.
作者
白日兰
李汶倩
陈菲
闫旭
崔久嵬
BAI Rilan;LI Wenqian;CHEN Fei;YAN Xu;CUI Jiuwei(Cancer Center,the First Hospital of Jilin University,Changchun,Jilin 130021,China)
出处
《重庆医学》
CAS
2020年第11期1746-1749,共4页
Chongqing medicine
基金
吉林省财政厅项目(2018SCZWSZX-010)
吉林省科技厅科技发展计划项目(20190303146SF)
吉林省发展和改革委员会省级产业创新专项资金项目(2017C022)
吉林省科技厅重点实验室建设项目(20170622011JC)。
