早期乳腺癌麦默通微创旋切活检术后病灶残留的影响因素分析

Influencing factors for residual lesions after minimally invasive rotary biopsy of Maimotong in early breast cancer

目的分析早期乳腺癌麦默通微创旋切活检术后病灶残留的影响因素。方法回顾性分析行麦默通微创旋切活检术切除肿块后病理确诊为早期乳腺癌的143例患者临床资料,根据乳腺癌根治性手术术后是否有病灶残留,分为完全切除组(57例)与未完全切除组(86例),对可能影响乳腺癌病灶残留的因素进行分析。结果乳腺癌病灶残留与患者年龄、肿瘤大小、回声模式、临床分期、Ki-67表达及HOXB9表达密切相关(P<0.05),回声模式、Ki-67表达及HOXB9表达是乳腺癌病灶残留的独立危险因素(P<0.05)。结论早期乳腺癌麦默通微创旋切活检术后病灶残留率偏高,目前技术水平还无法替代传统保乳术,今后可通过严格控制手术适应证的方式来减少甚至避免病灶残留,以提高患者远期生存率。

Objective To analyze the influencing factors for residual lesions after the minimally invasive rotary biopsy of Maimotong in early breast cancer.Methods Clinical data of 143 patients confirmed early breast cancer pathologically and underwent minimally invasive rotary biopsy of Maimotong to remove the mass were collected retrospectively.According to whether there were residual lesions after surgery,they were divided into the complete resection group(57 cases)and the incomplete resection group(86 cases).Factors that may affect residual lesions in breast cancer were analyzed.Results Breast cancer residual lesions are closely related to patients age,tumor size,echo pattern,clinical stage,Ki-67 expression and HOXB9 expression(P<0.05).Echo pattern,Ki-67 expression and HOXB9 expression are independent risk factors for breast cancer residual lesions(P<0.05).Conclusion The postoperative residual rate of minimally invasive rotary resection biopsy of Maimotong in early breast cancer is high,which cannot replace traditional breast-conserving surgery.In the future,strict control of surgical indications can be used to reduce or even avoid residual lesions,and improve the long-term survival rate of patients.