双能量CT及DWI食管癌病理分级对照

The preliminary application of dual energy CT and MRI diffusion weighted imaging in the pathological grade of esophageal cancer

目的:探讨双能量CT及DWI在食管癌病理分级中的应用价值。方法:搜集60例食管癌患者行CT及MRI检查,分别测量CT动、静脉期病灶的NIC、CT强化程度及ADC值,比较食管癌不同分化程度间NIC值、CT强化程度及ADC的差异;对不同分化程度NIC值、ADC值行ROC曲线分析。结果:不同分化程度食管癌NIC值及CT强化程度不同,各组间动静脉期NIC及静脉期CT强化程度差异均有统计学意义(P<0.05),而动脉期CT强化程度差异无统计学意义(P>0.05);动、静脉期NIC值及ADC值诊断中高分化食管癌与低分化食管癌ROC曲线下面积分别为0.801、0.817、0.816。结论:双源CT碘浓度及DWI成像ADC值能反映出食管癌的病理分级,可为临床分期、治疗及预后评价提供更多信息。

Objective:This study aimed to investigate the preliminary application of dual energy CT and MRI diffusion weighted imaging in the pathological grade of esophageal cancer.Methods:60 cases of esophageal cancer all underwent the examination of dual energy CT and MRI.The normalization iodine concentration(NIC)values and the degree of CT enhancement of esophageal cancer were measured respectively at arterial phase and the venous phase,and the ADC value of DWI imaging was measured.The difference of NIC values and ADC value among different pathological grades of esophageal cancer were compared,and also analyzed by ROC curve.Results:The NIC values and the degree of CT enhancement in different pathological grading esophageal cancer were different,the differences of NIC at arterial phase and venous phase and the degree of CT enhancement at venous phase between groups were statistically significant(P<0.05).But the degree of CT enhancement among different differentiated esophageal cancer demonstrated no statistically significant difference at arterial phase(P>0.05);ROC curve analysis,the NIC value of arterial and venous phase values and ADC values in the diagnosis of esophageal cancer high differentiation and low differentiation of esophageal area under the ROC curve were 0.801,0.817,0.816.Conclusions:The dual-source CT iodine concentration and the ADC value can reflect the pathological classification of esophageal cancer to some extent,which can provide more information for the clinical stage,treatment and prognosis evaluation of esophageal cancer.