神经元特异性烯醇化酶在小儿前纵隔恶性淋巴瘤诊断中的临床价值

Clinical value of neuron-specific enolase in the diagnosis of anterior mediastinal malignant lymphoma in children

目的探究神经元特异性烯醇化酶在小儿前纵隔恶性淋巴瘤诊断中的临床价值。方法入组2017年6月至2019年10月我院收治的30例小儿前纵隔恶性淋巴瘤作为观察组,同时选取同一时间内于我院接受治疗的其他纵隔肿瘤患儿30例作为对照组,比较观察2组患儿血清神经元特异性烯醇化酶水平。结果观察组患儿血清神经元特异性烯醇化酶水平为(75.39±8.17)μg/L,明显高于对照组患儿的(22.78±7.29)μg/L,差异有统计学意义(P<0.05)。结论神经元特异性烯醇化酶在小儿前纵隔恶性淋巴瘤诊断中显示出了较高的价值。

Objective To explore the clinical application value of neuron-specific enolase in the diagnosis of anterior mediastinal malignant lymphoma in children.Methods The study was carried out from June 2017 to December 2019,30 children with anterior mediastinal malignant lymphoma admitted in our hospital during this period,and were selected as the observation group;30 children with other tumors treated in our hospital at the same time were selected as the control group.The serum neuron-specific enolase levels were compared between the two groups.Results The serum neuron-specific enolase level in the observation group was(75.39±8.17)μg/L,and the neuron-specific enolase level in the control group was(22.78±7.29)μg/L(P<0.05).Conclusion Neuron-specific enolase has shown high sensitivity in the diagnosis of anterior mediastinal malignant lymphoma in children.