广州市3岁以下儿童血清维生素A水平调查分析

Investigation of serum vitamin a level among under-three children in Guangzhou

目的分析广州市3岁以下儿童维生素A水平,评价儿童维生素A营养状况。方法选择2018年11月-2019年4月在广东省妇幼保健院儿童保健门诊常规健康检查的2792名6~30月龄儿童为研究对象;通过LK3000V维生素检测仪电化学法检测血清维生素A水平。结果6~30月龄儿童平均维生素A水平(0.63±0.20)μmol/L;6月龄组(0.62±0.20)μmol/L和12月龄组(0.63±0.20)μmol/L均低于24月龄以上组(0.66±0.21)μmol/L儿童维生素A水平,差异具有统计学意义(F=4.117,P=0.006);总体维生素A缺乏比例33.1%,其中6月龄组最高(36.2%),随年龄增加而下降(χ^2=4.564,P=0.033);维生素A缺乏率随儿童BMI增加呈上升趋势,但差异无统计学意义。结论广州地区3岁以下儿童维生素A缺乏率较高,与年龄呈负相关,应提高对低年龄阶段儿童维生素A缺乏问题的重视。

Objective This study was to evaluate the serum vitamin A level among under-three children in Guangzhou.Methods A total of 2792 children aged 6-30 months who received physical examination in children’s health clinic during Nov 2018 to Apr 2019 were selected as subjects.Serum vitamin A levels were measured by electrochemical method using LK3000 V.Results The mean serum vitamin A levels was 0.63±0.20μmol/L.Serum vitamin A in children aged 6 months(0.62±0.20μmol/L)and in children age 12 months(0.63±0.20μmol/L)were lower than that in children aged 24 months(0.66±0.21μmol/L),which showed significant differences(F=4.117,P=0.006).The overall prevalence of vitamin A deficiency was 33.1%.The highest prevalence of vitamin A deficiency was found in the 6 months age group(36.2%).The prevalence of vitamin A deficiency were decreased with children’s age(χ^2=4.564,P=0.033).The prevalence of vitamin A deficiency had a increased trend with children’s BMI,but there was no significant difference among different groups.Conclusions The prevalence of vitamin A deficiency is high among children under 3 years in Guangzhou,which is negatively correlated with children’s age.More attention should be payed to vitamin A deficiency,especially in low age group.