探讨登革热患者的临床检验结果特征

Explore the Characteristics of Clinical Test Results in Patients with Dengue Fever

目的研究分析针对登革热患者的临床检验结果以及特征。方法选取150例该院在2019年1—10月收治的疑似登革热患者,所有患者中阳性患者108例,阴性患者42例;将所有患者按照年龄随机分为3组,其中0~13岁患者15例,14~50岁患者85例,51岁以上的患者50例;对3组患者的临床检验结果特征进行对比分析。结果经过相关临床检验后发现,0~13岁患者中的阳性率为40.00%,14~50岁患者的阳性率为82.35%,51岁以上的患者阳性率为64.00%;组间差异有统计学意义(P<0.05);且108例阳性患者中出现白细胞计数(WBC)降低患者为78例,总占比72.22%;出现血小板计数(PLT)降低患者为40例,总占比37.04%;出现中性粒细胞百分比下降患者为35例,总占比32.41%;其中血清丙氨酸氨基转移酶升高患者62例,总占比57.41%;天冬氨酸氨基转移酶升高患者32例,总占比29.63%;肌酐异常的患者28例,总占比25.93%;血清尿素升高患者18例,总占比16.67%;均显著高于42例阴性登革热患者,组间差异有统计学意义(P<0.05)。结论登革热的主要发病人群为14~50岁间的患者,年龄较以往报道偏大,另外,白细胞计数(WBC)和血小板计数(PLT)均可以作为登革热患者的诊断筛查依据。

Objective To analyze the clinical test results and characteristics of patients with dengue fever.Methods 150 cases of suspected dengue patients admitted in the hospital from January to October 2019 were selected.Among all the patients,108 were positive and 42 were negative.All patients were randomly divided into three groups according to age,15 patients were 0-13 years old,85 patients were 14-50 years old,and 50 patients were 51 years old or older.The characteristics of clinical test results of the three groups were compared and analyzed.Results After relevant clinical tests,it was found that the positive rate among patients aged 0-13 was 40.00%,the positive rate among patients aged 14-50 years was 82.35%,and the positive rate among patients over 51 years was 64.00%,the difference was statistically significant(P<0.05);and among the 108 positive patients,there were 78 patients with reduced white blood cell count(WBC),accounting for 72.22%;40 patients with decreased platelet count(PLT),accounting for 37.04%;there were 35 patients with decreased neutrophil percentage,accounting for 32.41%;62 patients with elevated serum alanine aminotransferase,accounting for 57.41%;32 patients with elevated aspartate aminotransferase,total Accounting for 29.63%;28 patients with abnormal creatinine,a total ratio of 25.93%;18 patients with elevated serum urea,a total ratio of 16.67%;significantly higher than 42 patients with negative dengue,the differences between groups were significant,the difference was statistically significant(P<0.05).Conclusion The main population of dengue fever is patients between the ages of 14-50 years old,which is older than previously reported.In addition,white blood cell count(WBC)and platelet count(PLT)can be used as the basis for the diagnosis and screening of dengue fever patients.