尼可地尔对高龄冠心病不稳定型心绞痛患者临床疗效价值

Clinical Efficacy of Nicorandil in the Elderly Patients With Unstable Angina Pectoris

目的观察和探讨尼可地尔对高龄冠心病不稳定型心绞痛患者的临床疗效。方法选择于2018年1月—2019年12月来本院就诊的冠心病不稳定型心绞痛100例高龄患者作为研究对象,通过随机数字表法分为观察组和对照组两组,每组50例患者。对对照组患者进行常规的治疗,对观察组患者在对照组基础上给予尼可地尔。对两组患者的有效率,心绞痛的改善指标(发作次数和每次发作持续时间)和不良反应进行对比分析。结果观察组患者的临床有效率,心绞痛的发作次数和每次发作持续时间的改善程度均显著优于、不良反应发生率显著低于对照组患者,差异均具有统计学意义(P<0.05)。结论尼可地尔对高龄冠心病不稳定型心绞痛患者的临床疗效确切,显著改善了心绞痛的发作次数和每次发作持续时间,不良反应低。

Objective To observe and explore the clinical effect of nicorandil on the elderly patients with unstable angina pectoris.Methods A total of 100 elderly patients with unstable angina pectoris of coronary heart disease who were admitted to our hospital from January 2018 to December 2019 were selected as the study objects.they were divided into two groups by the random number table method,the observation group and the control group,each group had 50 patients.The patients in the observation group were given nidil on the basis of the control group.To observe and compare the clinical efficiency,the number of angina attacks,the duration of each attack and adverse reactions of the two groups.Results The clinical effective rate,the number of angina attacks and the improvement of the duration of each attack in the observation group were better than those of the control group,and the incidence of adverse reactions in the observation group was significantly lower than that in the control group(14%),the difference was statistically significant(P<0.05).It is consistent with the results reported in the literature.Conclusion The clinical effect of nicorandil on the elderly patients with unstable angina pectoris of coronary heart disease is accurate,and it can significantly improve the attack frequency and duration of each attack,with low adverse reactions.