肠道菌群与内分泌疾病

Intestinal flora and endocrine diseases

肠道菌群是一个庞大且复杂的微生物群落,位于人体胃肠道生态系统中,作为人体内一个隐藏的内分泌器官,肠道菌群失调不仅影响各种肠道疾病,还会导致代谢异常的发生,例如糖尿病、肥胖、代谢综合征等。越来越多的研究表明,肠道菌群与内分泌疾病的发生、发展息息相关,其中肠道菌群与糖尿病的研究最多,被广泛关注,而对于其他内分泌疾病与肠道菌群的相关性还认识不足。从内分泌各腺体角度总结和讨论当前的发现,以阐明肠道菌群在内分泌疾病发展中的作用及潜在的机制,可能会为疾病的治疗策略提供新的见解。

Intestinal flora is a large and complex microbial community located in the human gastrointestinal ecosystem.As a hidden endocrine organ in the human body,the imbalance of intestinal flora affects not only various intestinal diseases,but also metabolic diseases,such as diabetes,obesity,metabolic syndrome and so on.More and more studies have shown that intestinal flora is closely related to the occurrence and development of endocrine diseases,among which intestinal flora and diabetes are most studied and widely concerned,while the correlation between other endocrine diseases and intestinal flora is still poorly understood.The current findings from the perspective of endocrine glands can clarify the role of intestinal flora in the development of endocrine diseases and its potential mechanism,which may provide new insights for the treatment strategies of diseases.