肌内效贴对延迟性肌肉酸痛影响的Meta分析

A meta-analysis of kinesio taping in the treatment of delayed onset muscle soreness

背景:既往研究显示肌内效贴对延迟性肌肉酸痛疗效尚不一致。目的:运用Meta分析方法综合定量评价肌内效贴对延迟性肌肉酸痛的疗效,旨在为此技术的临床应用提供理论依据。方法:检索从中国知网、万方数字资源数据库、Web of Science、PubMed、EBSCO等数据库中关于肌内效贴治疗延迟性肌肉酸痛的随机对照试验,检索时限从数据库建库至2019年10月。采用Cochrane协作网中随机对照试验偏倚风险评价标准进行方法学质量评估,采用RevMan 5.3软件进行Meta分析。采用Stata 15.0进行Meta回归分析。结果与结论:最终纳入9项随机对照试验,共382例患者。Meta分析发现,肌内效贴组主观疼痛评分(目测类比评分)明显低于无刺激组[SMD=-0.85,95%CI(-1.32,-0.39),P=0.0003],肌内效贴组肌酸激酶水平较无刺激组差异无显著性意义[SMD=0.30,95%CI(-0.17,0.76),P=0.21];与假刺激组相比,主观疼痛评分[SMD=-0.20,95%CI(-0.46,0.06),P=0.13]和肌酸激酶水平[SMD=0.22,95%CI(-0.06,0.49),P=0.12]差异均无显著性意义。提示肌内效贴可能有利于减轻延迟性肌肉酸痛患者主观疼痛程度,其疗效存在安慰剂效应。

BACKGROUND:Previous studies have shown the inconsistent efficacy of kinesio taping on delayed onset muscle soreness.OBJECTIVE:To quantitatively evaluate the effect of kinesio taping on delayed onset muscle soreness by means of Meta-analysis,in order to provide theoretical basis for the clinical application of this technique.METHODS:Randomized controlled trials of kinesio taping for treatment of delayed onset muscle soreness was retrieved from CNKI,WanFang,Web of Science,PubMed,EBSCO and other databases.The retrieval time was from inception to October 2019.The risk assessment criteria for RCT bias in the Cochrane collaboration were used for methodological quality assessment,and the RevMan 5.3 software was used for Meta-analysis.Meta-regression analysis was performed using Stata 15.0.RESULTS AND CONCLUSION:Nine RCTs were finally included,with a total of 382 patients.Meta-analysis results showed that the subjective pain score(visual analogue scale)in the kinesio taping group was significantly lower than that in the non-stimulation group[standard mean difference(SMD)=-0.85,95%confidence interval(CI)(-1.32,-0.39),P=0.0003],and the creatine kinase level in the kinesio taping group was not significantly different from that in the non-stimulation group[SMD=0.30,95%CI(-0.17,0.76),P=0.21].Compared with the false stimulation group,the kinesio taping group showed no significant difference in the subjective pain score[SMD=-0.20,95%CI(-0.46,0.06),P=0.13)]and creatine kinase level[SMD=0.22,95%CI(-0.06,0.49),P=0.12].It suggests that kinesio taping may be beneficial to reduce subjective pain in patients with delayed onset muscle soreness,and there is a placebo effect.