中西医联合心理干预治疗寻常性银屑病临床观察

Clinical study of traditional Chinese and western medicine combined with psychotherapy therapy on psoriasis vulgaris

目的观察中西医联合心理干预治疗寻常性银屑病的临床疗效。方法选取146例寻常性银屑病患者随机分为试验组和对照组,试验组给予中西医联合心理干预治疗,对照组给予复方丙酸氯倍他索软膏治疗,随访8周,统计分析患者银屑病皮损面积和严重程度指数(PASI)评分、皮肤病生活质量指数(DLQI)评分、有效率。结果 2组治疗后PASI评分较治疗前均显著降低,且差异有统计学意义(P <0.01),但试验组与对照组比较,PASI评分差异均无统计学意义(P> 0.05);试验组及对照组治疗后DLQI评分均较治疗前显著降低,且差异有统计学意义(P <0.01);治疗后试验组DLQI评分较对照组低,差异有统计学意义(P <0.05)。试验组和对照组治疗后有效率分别为88.00%、85.92%,差异无统计学意义(χ^2=0.14,P> 0.05)。结论中西医联合心理干预治疗寻常性银屑病疗效确切,且可有效改善患者生活质量。

Objective To observe the clinical effect of psychological intervention combined with traditional Chinese and western medicine on psoriasis vulgaris. Methods 146 patients with psoriasis vulgaris were randomly divided into the treatment group and the control group. The treatment group was given psychological intervention combined with traditional Chinese and western medicine. The control group was given clobetasol propionate compound. All the patients were followed for 8 weeks. The patients with psoriasis area and severity index(PASI) score, dermatology life questionnaire index(DLQI) and effective rate were analyzed.Results After treatment, the PASI scores in the two groups were much decreased compared with those before treatment and the difference was statistically significant(P < 0.01). However, there was no significant difference in PASI score between the treatment group and the control group(P > 0.05). The DLQI scores of the treatment group and the control group were significantly lower after treatment than before, and the difference was statistically significant(P < 0.01). After treatment, the DLQI score of the treatment group was lower than that of the control group, and the difference was statistically significant(P < 0.05). The effective rates of the treatment group and the control group were 88.00% and 85.92%, respectively, there was no significant difference between the treatment group and the control group(χ^2=0.14, P > 0.05). Conclusion Psychological intervention combined with traditional Chinese and western medicine is effective in the treatment of psoriasis vulgaris, and can effectively improve the quality of life of patients.