摘要
带状疱疹是由潜伏在体内的水痘-带状疱疹病毒再激活引起的一种急性皮肤病,主要发生于老年人等免疫力低下人群。带状疱疹是一种自限性疾病,临床主要表现为带状、成片的皮疹,而其后遗神经痛为该病中最复杂且最常见的不良并发症。带状疱疹的发病机制较为复杂,推测与机体的特异性T细胞免疫水平降低有关。本文就带状疱疹与T细胞之间的关系,最新疫苗研究进展进行综述,为疫苗的研发及带状疱疹的预防提供参考。
Herpes zoster is an acute skin disease caused by relapse of varicella-zoster virus,which mainly occurs in the elderly and people with low immunity.Herpes zoster is a self-limiting disease characterized by rashes.Postherpetic neuralgia is the most complex and common adverse complication of herpes zoster.The pathogenesis of herpes zoster is complex,presumably related to T cell immunity.In this paper,the relationship between herpes zoster and T cells,along with the latest vaccine research,is reviewed.
作者
李计来
徐静
LI Jilai;XU Jing(No.3 Research Laboratory,National Vaccine and Serum Institute,Beijing 101111,China)
出处
《微生物与感染》
2020年第3期186-191,共6页
Journal of Microbes and Infections
