摘要
头孢菌素是一种常用的抗生素药物,结晶操作是其制备环节的重要组成部分,合适的结晶方式与结晶工艺的选取也是制备高质量头孢菌素药物的必要条件。本文以不同代数头孢菌素为分类基础,总结了头孢菌素结晶过程中所采用的结晶方式。
Cephalosporin is a kind of commonly used antibiotic drugs.Crystallization operation is an important part of the preparation of cephalosporin The selection of appropriate crystallization method and the crystallization process is also a necessary condition for the preparation of high-quality cephalosporin drugs.Based on the classification of cephalosporin in different algebras,the crystallization methods of cephalosporin were summarized in this paper.
作者
陈辉
李刚
程燕
刘玉智
郝翠
孙芸芸
Chen Hui;Li Gang;Cheng Yan;Liu Yuzhi;Hao Cui;Sun Yunyun(Shandong Analysis and Test Center,Qilu University of Technology(Shandong Academy of Science),Jinan 250014,China;Shandong University of Finance and Economics,Physical Education College,Jinan 250014,China;Shandong Qingke Environmental Technology Co.,Ltd.,Jinan 250014 China)
出处
《山东化工》
CAS
2020年第9期89-90,共2页
Shandong Chemical Industry
基金
国家自然科学基金(21703126)
山东省重点研发计划(2018GSF117006,2019GSF109063)
山东社科规划项目《体育专业大学生就业价值取向变化特点及引导研究》(17CTYJ21)。
关键词
头孢菌素
结晶
抗生素
cephalosporin
crystallization
antibiotics
