一氧化氮与代谢综合症相关性的研究进展

Research Progress on the Relationship Between Nitric Oxide and Metabolic Syndrome

代谢综合症(MS)是代谢系统疾病中一组慢性进行性疾病,高血脂症、高血压及肥胖是其主要的病因。一氧化氮(NO)作为重要的细胞信使和效应分子,它介导并调节多种机体代谢功能,同时一氧化氮合酶(NOS)是NO合成过程中的关键酶,现就NO的功能特性及其参与MS相关疾病诊治的研究进展进行概述。

Metabolic syndrome(MS)is a group of chronic progressive diseases in the metabolic system.Hyperlipidemia,hypertension and obesity are the main causes.Nitric oxide(NO),as an important cellular messenger and effector molecule,mediates and regulates various metabolic functions of the body.At the same time,nitric oxide synthase(NOS)is a key enzyme in the process of NO synthesis.The research progress of its participation in the diagnosis and treatment of MS-related diseases is summarized.