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血清糖化血红蛋白水平对急性心肌梗死患者远期疗效的预测价值

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摘要 目的研究急性心肌梗死患者血清糖化血红蛋白(HbA1c)水平对远期预后的预测价值。方法回顾性分析笔者所在医院2015年5月—2017年5月收治的急性心肌梗死患者72例(急性心肌梗死组),再参照《2013年ADA糖尿病诊疗指南修订汇总》相关标准,根据患者血清HbA1c含量分为正常组(HbA1c≤6.4%)43例和升高组(HbA1c≥6.5%)29例。选择同期不稳定型心绞痛患者72例(不稳定型心绞痛组)及正常常规体检健康人群72例(对照组)。收集所有患者的临床资料,测定入院当天血清HbA1c、空腹血糖(fasting blood-glucose,FBG)、血浆纤维蛋白原(fibrinogen,FIB)含量,并对急性心肌梗死组实施为期1年随访调查(截至2018年5月),随访终点事件为主要不良心脏事件(Major Adverse Cardiac Events,MACE)。结果急性心肌梗死组入院时,HbA1c、FBG、FIB含量均明显高于不稳定型心绞痛组和对照组(P<0.05)。急性心肌梗死患者中HbA1c正常组随访1年,MACE发生率明显低于升高组(P<0.05)。二分类Logistic回归分析结果显示,HbA1c含量升高是急性心肌梗死患者MACE事件独立危险因素(P<0.05)。结论血清HbA1c水平对急性心肌梗死患者远期预后有一定的预测价值。
作者 丁红娜
出处 《实用医药杂志》 2020年第6期513-515,共3页 Practical Journal of Medicine & Pharmacy
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  • 1刘文兵,方快发,张亦辉,林佩环.高血糖对老年急性ST段抬高心肌梗死急诊介入治疗患者心功能及预后的影响[J].中国老年学杂志,2015,35(2):495-496. 被引量:5
  • 2李小鹰.阿司匹林在动脉硬化性心血管疾病中的临床应用:中国专家共识(2005)[J].中华心血管病杂志,2006,34(3):281-284. 被引量:194
  • 3Braunwald E, Antman EM, Beasley JW, et al. ACC/AHA 2002 guideline update for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction-summary article: a report of the American College of Cardiology/American Heart Association task force on practice guidelines(Committee on the Management of Patients With Unstable Angina). J Am Coll Cardiol,2002, 40(7) :1366-1374.
  • 4Bertrand ME, Simoons ML, Fox KA, et al. Management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. Eur Heart J,2002,23 ( 23 ) : 1809 -1840.
  • 5Erhardt L, Herlitz J, Bossaert L, et al. Task force on the management of chest pain. Eur Heart J, 2002, 23 ( 15 ) : 1153-1176.
  • 6CAPRIE Steering Committee. A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). CAPRIE Steering Committee. Lancet, 1996, 348(9038) :1329-1339.
  • 7Yusuf S, Zhao F, Mehta SR, et al. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med, 2001 , 345 ( 7 ) :494-502.
  • 8Mehta SR, Yusuf S, Peters RJ, et al. Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: the PCI-CURE study. Lancet, 2001, 358(9281):527-533.
  • 9Simoons ML, GUSTO IV-ACS Investigators. Effect of glycopmtein Ⅱb/Ⅲa receptor blocker abciximab on outcome in patients with acute coronary syndromes without early coronary revascularisation:the GUSTO IV-ACS randomised trial. Lancet, 2001,357(9272) :1915-1924.
  • 10Platlat Receptor Inhibitor in Ischemic Syndrome Management(PRISM) study investigator. A comparison of aspirin plus tirofiban with aspirin plus heparin for unstable angina. Platelet Receptor Inhibition in Ischemic Syndrome Management ( PRISM )Study Investigators. N Engl J Med, 1998, 338(21 ) :1498-1505.

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