多发性硬化的干细胞治疗进展

Advances in multiple sclerosis stem cell therapy

多发性硬化是一种严重的神经系统炎症性疾病,其发病机制尚未完全明确。通过免疫消融随后自体造血干细胞移植的方法能有效缓解多发性硬化动物模型的症状和预后,可能成为临床上治疗多发性硬化的新方法。故就多发性硬化的干细胞治疗进展进行综述,为多发性硬化的诊断和治疗提供新思路。

Multiple sclerosis is a serious inflammatory disease of the nervous system,and its pathogenesis has not been fully clarified.Immunoablation followed by autologous hematopoietic stem cell transplantation can effectively alleviate the clinical symptoms and prognosis of multiple sclerosis in animal models,and may become a new method for clinical treatment of multiple sclerosis.This article reviews the progress of stem cell therapy for multiple sclerosis and provides new ideas for the diagnosis and treatment of multiple sclerosis.