经宫腔镜输卵管加压通液结合口服中药治疗输卵管炎性阻塞性不孕症的临床疗效观察

Clinical observation of hysteroscopic intubation combined with traditional Chinese medicine in the treatment of tubal inflammatory obstructive infertility

目的观察经宫腔镜输卵管加压通液结合口服中药治疗输卵管炎性阻塞性不孕症的临床疗效,为输卵管炎性阻塞性不孕症治疗提供参考。方法选取2017年1月至2017年12月海宁市第二人民医院中医妇科门诊诊治的352例输卵管炎性阻塞性不孕症患者作为研究对象。随机分为研究组(172例)和对照组(180例),对照组采取单纯输卵管加压通液治疗,研究组在此基础上加口服中药治疗,并分析比较两组患者的临床疗效。结果研究组显效109例(63.4%)、有效44例(25.6%)、无效19例(11.0%)、总体有效率89.0%,对照组显效64例(35.6%)、有效58例(32.2%)、无效58例(32.2%)、总体有效率67.8%,两组间总体有效率比较差异具有统计学意义(P=0.007);研究组输卵管输卵管复通率89.0%高于对照组68.1%,两组间比较差异具有统计学意义(P<0.05);研究组宫内妊娠103例(59.9%),对照组宫内妊娠54例(30.0%),两组患者宫内妊娠比较差异具有统计学意义(P<0.05)。结论经宫腔镜输卵管加压通液通液结合口服中药治疗输卵管炎性阻塞性不孕症的临床疗效显著,有效提高患者妊娠率,值得临床推广。

Objective To observe the clinical effect of hysteroscopic intubation combined with traditional Chinese medicine in the treatment of tubal inflammatory obstructive infertility,in order to provide references for the treatment of tubal inflammatory obstructive infertility.Methods From January 2017 to December 2017,352 cases of tubal inflammatory obstructive infertility diagnosed in Haining Second People′s Hospital were selected and randomly divided into study group(n=172)and control group(n=180).The control group was treated by simple hysteroscopic intubation,while the study group was treated by hysteroscopic intubation and traditional Chinese medicine.The clinical effects of the two groups were compared.Results In the study group,there were 109 cases(63.4%)remarkably effective,44 cases(25.6%)effective and 19 cases(11.0%)ineffective,and the overall effective rate was 89.0%.In the control group,there were 64 cases(35.6%)remarkably effective,58 cases(32.2%)effective and 58 cases(32.2%)ineffective,and the overall effective rate was 67.8%.There was a statistical difference in the overall effective rate between the two groups(P=0.007).The intraoperative recanalization rate in the study group(89.0%)was significantly higher than that in the control group(68.1%),with statistically significant differences(P<0.05).There were statistically significant differences in the intrauterine pregnancy rate between the study group(103 cases,59.9%)and the control group(54 cases,30.0%)(P<0.05).Conclusions Hysteroscopic intubation combined with oral Chinese medicine is of remarkable effect in the treatment of tubal inflammatory obstructive infertility,which can effectively improve the pregnancy rate of patients and is worthy of clinical promotion.