反复子宫脱垂对宫颈及阴道病变进展的影响

Effect of Repeated Uterine Prolapse on Progression of Cervical and Vaginal lesions

[目的]探讨反复子宫脱垂对宫颈及阴道病变进展的影响.[方法]选择2015年1月30日至2016年6月30日在本院诊治的100例反复子宫脱垂患者(观察组),选择同期本院健康体检者100例作为对照组,比较两组受试者宫颈长度(前后径及横经)及宫颈阴道部长度.随访3年,观察两组宫颈病变及阴道炎发生率,并分析其与宫颈大小及宫颈阴道部长度关系.[结果]观察组宫颈增大及宫颈阴道部延长发生率显著高于对照组,且随访期间新发宫颈增大及宫颈阴道部延长比例高于对照组,差异均有统计学意义(P<0.05).随访3年后,观察组宫颈病变及阴道炎发生率均显著高于对照组(P<0.05).观察组宫颈病变及阴道炎发生率与子宫脱垂分级具有相关性(P<0.05),Ⅳ度子宫脱垂患者宫颈病变及阴道炎发生率高于Ⅰ、Ⅱ、Ⅲ度患者(P<0.05).随访前观察组宫颈增大患者宫颈病变发生率高于非宫颈增大患者,宫颈阴道部延长患者阴道炎发生率高于非宫颈阴道部延长患者(P<0.05).[结论]反复子宫脱垂可增加宫颈及阴道病变发生率,且宫颈及阴道病变发生与宫颈大小、宫颈阴道部长度及子宫脱垂分级密切相关.

[Obective]To investigate the efet of repeated uterine prolapse on the progression of cervical and vaginal lesions.[Methods]A total of 100 patients with repeated uterine prolapse admitted to our hospital from January 30,2015 to June 30,2016 were selected as the observation group.At the same period,100 healthy women who received physical examination in our hospital were selected as the control group.The length of the cervix(anterior posterior diameter and transverse)and the length of the cervicovaginal were measured.The cervical size and the length of the cervix were com-pared between the two groups.The subjects were followed up for 3 years.The incidence of cervical lesions and vaginitis were recorded.The relationship between cervical lesions and cervix length was analyzed.[Results]The incidence of cervical enlargement and cervical vaginal prolongation was higher in the observation group than in the control group(P<0.05);and the proportion of new cervical enlargement and cervical vaginal extension in the observation group was higher during the follow-up period than that in the control group(P<0.05).After 3 years of follow up,the incidence of cervical le-sions and vaginitis in the observation group were higher than those in the control group(P<0.05).The incidence of cer-vical lesions and vaginitis in the observation group was correlated with uterine prolapse grade(P<0.05).The incidence of cervical uterine prolapse and vaginitis in patients with grade IV was higher than that in patients with gradeⅠ,ⅡandⅡ(P<0.05).The incidence of cervical lesions in patiehts with cervical enlargement before the follow-up was higher than that in patients with non-cervical enlargement and the incidence of vaginitis in patients with cervical vaginal extension be-fore the follow-up was higher than that in patients with non-cervical vaginal extension(P<0.05).[Conclusion Repeated uterine prolapse can increase the incidence of cervical and vaginal lesions,and the occurrence of cervical and vaginal lesions is closely related to the size of the cervix,the length of the cervicovaginal and the uterus prolapse.