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前瞻性随机对照临床试验评估硅凝胶对术后切口瘢痕的抑制作用

prospective randomized controlled clinical Trial to evaluate the Inhibitory Effect of Silicone Gel on postoperative Incision Scar
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摘要 目的 初步研究硅凝胶对抑制整形美容手术后切口瘢痕增生的效果.方法 采用前瞻性随机对照临床试验的方法随机选取2017年1月-2018年1月在西安交通大学第二附属医院整形美容外科就诊行手术治疗的患者150例.实验组术后拆线后用自干型轻质硅凝胶治疗,对照组为拆线后不做特殊处理的空白对照.对两个组治疗2月、3月的瘢痕色泽、血管分布、柔软度、厚度等方面进行评分.结果 ①实验组的总体疗效明显优于对照组;②实验组的温哥华评分总分、柔韧度、血管分布、厚度、色泽等方面优于对照组;③组内比较治疗三个月效果与两个月效果比较无显著差异.结论 术后定期外敷硅凝胶对手术切口瘢痕的形成具有抑制作用. Objective To preliminarily investigate the effect of silicone gel on inhibiting the proliferation of incision scar after plastic surgery.Methods A prospective randomized controlled clinical trial was conducted to randomly select 150 patients who received surgical treatment in the Plastic surgery department of the Second Affiliated Hospital of Xi'an Jiaotong University from January 2017 to January 2018.The experimental group was treated with self-drying light silicone gel after postoperative suture removal,while the control group was the blank control group without special treatment after suture removal.The scar color,vascular distribution,softness,thickness and other aspects of treatment for 2 months and 3 months were scored in the two groups.Results The overall efficacy of the experimental group was significantly better than that of the control group.The total Vancouver score,flexibility,vascular distribution,thickness and color of the experimental group were superior to those of the control group.There was no significant difference between three months and two months.Conclusion Regular application of silicone gel can inhibit the formation of scar after operation.
作者 闫瑾 李小珍 YAN Jin;LI Xiaozhen(Department of Physical Examination,The Second Affiliated Hospital of Xi'an Jiaotong University,Xi'an Shaanxi 710004,China)
出处 《临床研究》 2020年第7期33-35,共3页 Clinical Research
关键词 硅凝胶 术后瘢痕 临床试验 silicone gel Postoperative scar clinical trials
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