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叶酸在蛋鸡体内吸收代谢及其机制研究进展 被引量:2

Advances in Absorption and Metabolism of Folate and Its Mechanism in Layers
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摘要 叶酸摄入不足是全球普遍存在的问题,人体叶酸水平过低增加贫血、胎儿畸形、心脑血管疾病、癌症和认知障碍的风险。然而,氧化型叶酸的摄入可能引起叶酸过量导致的潜在致病风险。氧化型叶酸可在蛋鸡体内转化为天然的5-甲基四氢叶酸形式并富集于鸡蛋中,使人体在摄入食物的同时,解决叶酸摄入不足问题。本文综述了叶酸在鸡蛋中的富集规律及其在肠道、肝脏、卵巢、肾脏中的吸收和代谢过程,阐释了叶酸在蛋鸡体内代谢调控机制,旨在为叶酸在蛋鸡中的进一步研究提供参考依据。 Insufficient folate intake is a global problem,and low levels of folate in the human body increase the risk of anemia,malformation,cardiovascular and cerebrovascular diseases,cancer and cognitive impairment.However,excessive intake of oxidized folic acid may cause a potential risk.The oxidized folic acid is conver⁃ted into a natural form of 5⁃methyltetrahydrofolate by the layers,so that the human can solve the problem of in⁃sufficient folic acid intake while ingesting food.This paper reviewed the folic acid enrichment rule in eggs and its absorption and metabolism in the intestine,liver,ovary and kidney,and the metabolic regulation mecha⁃nism of folate in layers was explained.The purpose of this paper was to provide theoretical basis for further re⁃search of folic acid in layers.
作者 孙丹丹 张军民 赵青余 秦玉昌 SUN Dandan;ZHANG Junmin;ZHAO Qingyu;QIN Yuchang(State Key Laboratory of Animal Nutrition,Institute of Animal Science,Chinese Academy of Agricultural Sciences,Beijing 100193,China;Scientific Observing and Experiment Station of Animal Genetic Resources and Nutrition in North China of Ministry of Agriculture and Rural Affairs,Institute of Animal Science,Chinese Academy of Agricultural Sciences,Beijing 100193,China)
出处 《动物营养学报》 CAS CSCD 北大核心 2020年第6期2467-2475,共9页 CHINESE JOURNAL OF ANIMAL NUTRITION
基金 北京市科委计划课题(Z181100009318008) 中国农业科学院科技创新工程协同创新任务主要农产品营养品质评价与调控项目(CAAS⁃XTCX20190025⁃8) 中国农业科学院科技创新工程项目(ASTIP⁃IAS12)。
关键词 叶酸 吸收 代谢 富集 蛋鸡 folate absorption metabolism enrichment layers
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