开颅夹闭术与介入栓塞术治疗大脑中动脉瘤的临床疗效对比研究

Clinical e fficacy of surgical options compared with endovascularin treatment of middle cerebral artery aneurysm

目的观察开颅夹闭术与介入栓塞术治疗大脑中动脉瘤的临床疗效。方法将102例诊断为大脑中动脉瘤的患者随机分为开颅夹闭术组和介入栓塞术组,每组51例。比较两组患者大脑中动脉瘤完全闭塞率、复发率、并发症发生率、平均住院时间、住院费用及手术预后的差异。结果开颅夹闭术组的完全闭塞率和复发率与介入栓塞术组比较,差异无统计学意义(P>0.05);开颅夹闭术组并发症发生率高于介入栓塞术组(P<0.05);介入栓塞术组的住院时间短于开颅夹闭术组(P<0.05),但介入栓塞术组的住院费用高于开颅夹闭术组(P<0.05);介入栓塞术组的预后良好率高于开颅夹闭术组(P<0.05)。结论血管内介入栓塞术和开颅夹闭术的治疗效果良好。血管内介入栓塞术的并发症发生率更低,住院时间更短且预后情况良好,但是手术费用高于开颅夹闭术。

Objective To observe the clinical e fficacy of surgical options and endovascular in treatment of middle cerebral artery aneurysm.Methods A total of 102 patients with middle cerebral artery aneurysm were randomly divided into the surgical options group and the endovascular group,51 cases in each group.The rate of complete occlusion,recurrence and complications,hospital length,hospital expense and postoperative recovery were compared between the two groups.Results There was no signi ficant di fference in the rate of complete occlusion and recurrence rate between the surgical options group and endovascular group(P>0.05);the patients of the surgical options group had signi ficantly higher rate of complications than the endovascular group(P<0.05);the hospital length in endovascular group were signi ficantly shorter than those of the surgical options group,while the hospital expense in endovascular group were significantly higher than those of the surgical options group(P<0.05);the rate of postoperative recovery of the endovascular group was 88.2%,which was significantly better than that of the surgical options group(72.5%)(P<0.05).Conclusion The clinical e fficacy of surgical options and endovascular are both significant.Embolization has lower incidence of complications,shorter hospital length and better prognosis,while the hospital expense is significantly higher than that of surgical options.