胰岛素治疗对妊娠期糖尿病患者生活质量及不良妊娠的影响

Effects of Insulin Therapy on Quality of Life and Adverse Pregnancy in Patients with Gestational Diabetes Mellitus

目的:探究胰岛素治疗对妊娠期糖尿病(gestational diabetes mellitus,GDM)患者生活质量及不良妊娠的影响。方法:选取2017年1月-2019年10月本院收治的GDM患者92例,随机分成对照组和研究组,每组46例。对照组采用常规治疗,研究组在对照组基础上采用胰岛素治疗。观察对比两组患者的血糖控制情况、治疗后的生活质量以及不良妊娠的发生情况。结果:治疗前,两组的HbA1c、FPG、2 h FPG比较,差异均无统计学意义(P>0.05);治疗后,研究组的HbA1c、FPG、2 h FPG均低于对照组,差异均有统计学意义(P<0.05)。治疗后,研究组的生理机能、生理职能、躯体疼痛、一般健康状况、精力、社会功能、情感职能、精神健康评分均高于对照组,差异均有统计学意义(P<0.05)。研究组的不良妊娠发生率低于对照组,差异有统计学意义(P<0.05)。结论:将胰岛素用于GDM患者的临床治疗中,不仅可有效控制患者体内的血糖水平,同时减少并发症的出现,提高患者的生活质量,还能减少不良妊娠情况的发生,值得推广应用。

Objective:To explore the effect of Insulin therapy on quality of life and adverse pregnancy in patients with gestational diabetes mellitus(GDM).Method:A total of 92 patients with GDM admitted to our hospital from January 2017 to October 2019 were selected,they were randomly divided into the control group and study group,46 cases in each group.The control group received routine treatment,while the study group received Insulin treatment on the basis of the control group.The blood glucose control,quality of life and adverse pregnancy were observed and compared between the two groups.Result:Before treatment,the difference of HbA1c,FPG and 2 h FPG between the two groups were not statistically significant(P>0.05);after treatment,HbA1c,FPG and 2 h FPG in the study group were all lower than those in the control group,with statistically significant differences(P<0.05).After treatment,the scores of physiological function,physiological function,physical pain,general health status,energy,social function,emotional function and mental health in the study group were all higher than those in the control group,the differences were statistically significant(P<0.05).The incidence of adverse pregnancy in the study group was lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion:In the clinical treatment of gestational diabetes patients,Insulin can not only effectively control the blood glucose level of patients,but also reduce the occurrence of complications,improve the quality of life of patients and reduce the occurrence of adverse pregnancy,therefore,it is worthy of promotion and application.