喉部感觉神经性疾病的诊疗进展

Advances of the treatments and diagnosis for sensory laryngeal neuropathy

咽喉的基本功能有呼吸、吞咽、发声和咳嗽等[1],这些功能离不开分布于咽喉部的神经支配(迷走神经、舌咽神经)。当炎症刺激、胃酸反流等外界因素或病毒感染、营养、代谢等内在因素影响咽喉部时,该区域感觉神经的功能或结构可能出现异常,从而出现咽喉部异物感、慢性咳嗽、黏液增多、干燥、灼痛、频繁清嗓等症状[2-3]。

Sensory laryngeal neuropathy(SLN) is a kind of peripheral neuropathy presenting globus pharyngeus, chronic cough, increased mucus, dry throat, sore throat, frequent clearing of the throat, etc. When the sensory nerve of the larynx is affected by chemical, biological, mechanical or nutritional factors. Because of its nonspecific signs and symptoms, SLN is easy to be misdiagnosed as chronic pharyngitis or laryngopharyngeal reflux disease. SLN was came up to ENT physician in recent years and there are rare systematic reports currently, therefore, this review aims to summarize the etiology, clinical manifestations, diagnosis and treatment of SLN, to raise awareness of this disease among our colleagues.