量化式目标锻炼联合全程精细化营养管理在血液病化疗患者中的应用

Effects of quantitative goal exercise combined with whole-process refined nutrition management on rehabilitation quality after chemotherapy for hematologic diseases

目的探讨量化式目标锻炼(QGE)联合全程精细化营养管理(WP-RNM)在血液病患者化疗后的康复质量管理中的应用。方法采用便利抽样法,选取首都医科大学附属北京朝阳医院2017年1月—2019年1月收治的125例血液病化疗患者作为研究对象,按干预方法差异将其分为A、B、C、D组,每组患者依次31、32、31、31例。A组采用常规干预,B组采用QGE,C组采用WP-RNM,D组采用QGE联合WP-RNM。比较4组患者干预前后的营养状况及生活质量。结果4组干预后的前白蛋白、白蛋白、转铁白蛋白及血红蛋白等营养学指标均提高,D组高于A、B、C组,差异有统计学意义(P<0.05)。干预后,D组PG-DGA评分低于其他3组,差异有统计学意义(P<0.05)。4组患者干预后的生活质量调查量表-30各维度得分均降低,D组的各维度得分低于A、B、C组,差异均有统计学意义(P<0.05)。结论血液病化疗后针对其病情科学、合理地实施QGE联合全程RNM能有效提升患者的营养摄入质量,改善患者的免疫功能和生活质量,有较好的辅助应用价值,可在血液病化疗期间进行针对性推广与应用。

Objective To explore application of quantitative goal exercise(QGE)combined with whole-process refined nutrition management(WP-RNM)in rehabilitation quality management after chemotherapy for hematologic diseasespatients.Methods By the convenient sampling method,a total of 125 patients with hematologic diseases who underwent chemotherapyand were admitted to Beijing Chaoyang Hospital,Capital Medical University from January 2017 to January 2019 were selected as research objects.The patients were divided into groups A,B,C and D according to the difference of intervention methods,with 31,32,31 and 31 cases in every group in turn.Group A was given routine intervention,group B was given QGE,group C was givenWP-RNM and group D was given QGE combined withWP-RNM.The nutritional status and quality of life of the 4 groups before and after intervention were compared.Results The nutritional indexes such as prealbumin,albumin,transferrin and hemoglobin of four groups after intervention were improved,group D was higher than those of groups A,B,and C,and the differences were statistically significant(P<0.05).Scored Patient-Generated Subjective Global Assessment scores of group D were lower than other groups,and the differences were statistically significant(P<0.05).The scores of all dimensions of Quality of Life Questionnaire-C30 after intervention of 4 groups were declined,the scores of each dimension of group D were lower than those of groups A,B,and C,and the differences were statistically significant(P<0.05).Conclusions The scientific and rational implementation of QGE combined with f WP-RNM for hematologic diseases after chemotherapy can effectively improve the nutritional intake quality of patients and improve the immune function and quality of life of patients,which has good auxiliary application value.It can be targeted for promotion and application during chemotherapy for hematologic diseases.