中药补阳还五汤治疗脑梗塞气虚血瘀证的疗效分析

Efficacy of the Buyang Huanwu decoction on cerebral infarction with the Qixu Xueyu syndrome

目的:探讨中药补阳还五汤治疗脑梗塞气虚血瘀证的疗效。方法:选择2017年12月-2019年5月期间本院收治的68例脑梗塞气虚血瘀证患者,根据治疗方式分为补阳还五汤组和常规组,各34例。常规组患者予常规西药治疗,补阳还五汤组在常规组基础上增加补阳还五汤治疗,对比两组神经功能缺损和中医症状积分改善情况,并对比两组生活质量和用药安全性。结果:治疗2周后和治疗1个月,补阳还五汤组美国国立卫生院卒中量表(Nationol Institutes of Health Stroke Scale,NIHSS)评分分别为(18.69±5.36)分、(14.06±5.69)分,均显著高于常规组的(22.32±4.96)分、(18.06±6.18)分,差异具有统计学意义(P <0.05);补阳还五汤组和常规组治疗后各阶段NIHSS评分均显著低于治疗前,差异具有统计学意义(P <0.05)。补阳还五汤组总有效率显著高于常规组,差异具有统计学意义(P <0.05)。补阳还五汤组治疗2周后神识为(1.83±0.72)分、语言为(2.13±0.86)分、面瘫为(0.69±0.31)分、眼征为(1.03±0.54)分、上肢瘫和指瘫为(3.58±1.69)分,各项中医症状积分均显著低于常规组[(3.06±1.43)分、(3.14±0.98)分、(0.98±0.23)分、(2.01±0.79)分、(5.03±1.52)分],差异具有统计学意义(P <0.05)。治疗2周后,补阳还五汤组生理机能为(18.06±3.15)分、生理职能为(20.31±4.18)分、躯体疼痛为(20.47±5.03)分、一般健康状况为(23.06±4.30)分和其他项目评分(62.35±4.03)分,均显著高于常规组[(14.03±4.06)分、(12.03±2.69)分、(16.03±4.57)分、(19.03±5.17)分、(51.03±4.99)分],差异具有统计学意义(P <0.05)。结论:脑梗塞气虚血瘀证患者在常规西药基础上联合补阳还五汤治疗,中医症状积分改善效果良好,同时可进一步提升神经功能缺损修复效果,促进患者更快、更好的改善神经功能,临床应用安全性可靠。

Objective:To investigate the curative effect of the Buyang Huanwu decoction(补阳还五汤)on the Qixu Xueyu(气虚血瘀)syndrome.Methods:68 patients with the Qixu Xueyu syndrome of cerebral infarction were selected and divided into two groups according to the treatment mode,34 cases in each.The patients in the routine group were treated with western medicine,and the patients in the Buyang Huanwu decoction group were treated with the Buyang Huanwu decoction more.The improvement of neurological deficit and TCM syndrome score in the two groups,and the quality of life and drug safety in the two groups were compared.Results:After two weeks and one month of treatment,the NIHSS scores in the Buyang Huanwu decoction group were significantly higher than(22.32±4.96)points,(18.06±6.18)points in the conventional group(P﹤0.05).NIHSS scores in the Buyang Huanwu decoction group and the conventional group were significantly lower than those before treatment(P﹤0.05).The total efficiency in the Buyang Huanwu decoction group was significantly higher than the conventional group(P﹤0.05).After 2 weeks of treatment,the scores of Shenzhi was(1.83±0.72),language was(2.13±0.86),facial paralysis was(0.69±0.31),eye sign was(1.03±0.54),upper limb paralysis and finger paralysis was(3.58±1.69)in the Buyang Huanwu decoction group,and those were significantly lower than(3.06±1.43),(3.14±0.98),(0.98±0.23),(2.01±0.79),(5.03±1.52)in the routine group,with stotistically significant differences(P﹤0.05).After two weeks of treatment,the scores of physiological function was(18.06±3.15)points,physiological function was(20.31±4.18)points,physical pain was(20.47±5.03)points,general health was(23.06±4.30)points and other items was(62.35±4.03)points in the Buyang Huanwu decoction group,and those were significantly higher than(14.03±4.06)points,(12.03±2.69)points,(16.03±4.57)points,(19.03±5.17)points,(51.03±4.99)points in the routine group,with stotistically significant differences(P﹤0.05).Conclusion:Conventional western medicine with the Buyang Huanwu decoction was effective by improving TCM syndrome scores and repairing nerve function defect,improving the nerve function,with safety.