介入治疗分支病变对主支病变血流储备分数影响

Effect of intervention into side branch lesion on flow fraction reserve of the main coronary artery stenosis

目的探讨介入治疗分支病变对主支病变血流储备分数(FFR)的影响。方法选取北部战区总医院2019年3-4月收治的4例行冠状动脉主支介入治疗时行冠脉造影显示有分叉病变的冠心病患者为研究对象。首先测定前降支病变FFR,然后对回旋支病变进行介入治疗,最后再次测定前降支病变FFR。结果 4例患者中,2例患者术后FFR升高,1例患者术后FFR降低,1例患者术前与术后FFR无明显变化。结论对于较大分支病变,治疗前后主支病变的FFR可能升高,可能降低,可能维持不变。在判断主支病变FFR时,应以较大分支病变治疗后测定值为准。

Objective To investigate the effect of intervention into side branch lesion on flow fraction reserve(FFR) of the main coronary artery stenosis.Methods A retrospective study was performed on four patients with side branch lesion during main coronary artery intervention from March to April 2019.First,FFR of anterior descending branch was measured,then interventional therapy was performed on circumflex branch,and then FFR of anterior descending branch was measured again.Results Among the 4 patients,FFR increased in 2 patients,FFR reduced in 1 patient,and there was no significant change in FFR before and after surgery in 1 patient.Conclusion For large branch lesions,FFR may increase,may reduce,and may remain unchanged in primary branch lesions before and after treatment.In determining the main branch lesion FFR,the post-treatment value of the larger branch lesion should prevail.