尼可地尔治疗冠心病患者介入治疗后心绞痛的临床疗效评价

Clinical Evaluation of Nicorandil in the Treatment of Angina Pectoris after Interventional Therapy in Patients with Coronary Heart Disease

目的探讨尼可地尔治疗冠心病患者介入治疗后心绞痛的临床疗效。方法选择我院80例2017年5月至2019年4月冠心病介入治疗后心绞痛患者。随机分组,常规治疗方案组对于冠心病介入治疗后心绞痛患者实施常规药物治疗,尼可地尔辅助治疗组对于冠心病介入治疗后心绞痛患者则实施常规药物+尼可地尔剂治疗。比较两组冠心病介入治疗后心绞痛疗效;病情好转的时间;治疗前后患者心功能监测指标;心绞痛发作次数。结果尼可地尔辅助治疗组冠心病介入治疗后心绞痛疗效、病情好转的时间、心功能监测指标相比较常规治疗方案组更好,P<0.05。尼可地尔辅助治疗组心绞痛发作次数显著少于和常规治疗方案组,P<0.05。结论常规药物+尼可地尔剂治疗冠心病介入治疗后心绞痛效果确切,可获得理想效果,可改善患者左心射血功能和运动耐受性,减少心绞痛发作。

Objective To investigate the clinical efficacy of nicorandil in the treatment of angina pectoris in patients with coronary heart disease after interventional therapy.Methods 80 patients with angina pectoris after percutaneous coronary intervention in our hospital from May 2017 to April 2019 were selected.Randomized grouping,routine treatment group for angina pectoris patients after interventional treatment of coronary heart disease routine drug treatment,nicorandil adjuvant treatment group for angina pectoris patients after interventional treatment of coronary heart disease routine drug plus nicorandil treatment.The curative effect of angina pectoris after interventional treatment of coronary heart disease,the time of improvement,the monitoring index of cardiac function before and after treatment,and the number of attacks of angina pectoris were compared between the two groups.Results The curative effect of angina pectoris after the interventional treatment of coronary heart disease,the time of improvement of the condition,and the cardiac function monitoring indexes of the nicorandil adjuvant treatment group were better than those of the conventional treatment group(P<0.05).The frequency of angina attack in nicorandil adjuvant treatment group was significantly less than that in routine treatment group(P<0.05).Conclusion Conventional medicine plus Nicorandil is effective in the treatment of angina pectoris after interventional therapy of coronary heart disease.It can obtain ideal effect,improve left ventricular ejection function and exercise tolerance,and reduce the attack of angina pectoris.