孕前妇女TORCH抗体、梅毒螺旋体抗体检测结果的分析

Analysis of detection results of TORCH antibody and treponema pallidum antibody in progestational women

目的分析孕前妇女TORCH抗体、梅毒螺旋体抗体(抗-TP)的检测结果。方法回顾性分析2018年1~12月大连市妇幼保健院接诊的100例孕前妇女的资料,比较孕前妇女不同季节、不同居住环境以及不同年龄段的TORCH感染情况。结果春、夏、秋、冬各季节组间的弓形虫IgM抗体(TOX-IgM)、风疹病毒IgM抗体(RV-IgM)、巨细胞病毒IgM抗体(CMV-IgM)、单纯疱疹病毒IgM抗体(HSV-IgM)和抗-TP阳性率比较,差异无统计学意义(P>0.05);冬、春季组的TOX-IgM、RV-IgM、CMV-IgM阳性率高于夏、秋季组,春季组的HSV-IgM阳性率高于秋季组,差异有统计学意义(P<0.05)。城镇、农村组的TOX-IgM、RV-IgM、CMV-IgM、HSV-IgM及抗-TP阳性率比较,差异无统计学意义(P>0.05)。20~25、>25~32、>32~38岁组的TOX-IgM、RV-IgM、CMV-IgM和HSV-IgM阳性率比较,差异无统计学意义(P>0.05);>32~38岁组的抗-TP阳性率高于>25~32、20~25岁组,差异有统计学意义(P<0.05)。结论孕前妇女具有一定TORCH以及梅毒感染率,TORCH有季节性特点,在春、冬季节注意预防TOX、RV和CMV感染,春季注意预防HSV感染,梅毒随年龄增大感染率上升,大龄妇女孕前应注意进行梅毒筛查及预防。

Objective To analyze detection results of TORCH antibody and treponema pallidum antibody(anti-TP)in progestational women.Methods A retrospective analysis was performed on the data of 100 progestational women who were treated in Dalian Maternal and Child Health Hospital from January to December 2018.TORCH infection conditions were compared among the progestational women in different seasons,different living environments and different age groups.Results There were no significant differences in positive rates of toxoplasma IgM antibody(TOX-IgM),rubella virus IgM antibody(RV-IgM),cytomegalovirus IgM antibody(CMV-IgM),herpes simplex virus IgM antibody(HSV-IgM)and anti-TP among spring,summer,autumn and winter group(P>0.05).The positive rates of TOX-IgM,RV-IgM and CMV-IgM in winter and spring group were higher than those in summer and autumn group,the positive rate of HSV-IgM in spring group was higher than that in autumn group,the differences were statistically significant(P<0.05).There were no significant difference in positive rates of TOX-IgM,RV-IgM,CMV-IgM,HSV-IgM and anti-TP among between urban and rural group(P>0.05).There were no significant difference in positive rates of TOX-IgM,RV-IgM,CMV-IgM or HSV-IgM among 20-25 years old group,>25-32 years old group and>32-38 years old group(P>0.05).The positive rate of anti-TP in>32-38 years old group was higher than that in>25-32 years old group and 20-25 years old group,the differences were statistically significant(P<0.05).Conclusion There are certain infection rates of TORCH and syphilis in progestational women.There are seasonal features of TORCH.TOX,RV and CMV infection should be prevented in spring and winter.HSV infection should be prevented in spring.The infection rate of syphilis is increased with age growing.Older women should pay attention to syphilis screening and infection prevention before pregnancy.