基于“气血学说”干预心梗后早期心室重构的探讨

Intervention of Early Ventricular Remodeling after Myocardial infarction Based on"Qi and blood theory"

心室重构是急性心肌梗死进展为心力衰竭的重要病理生理进程,其中,心梗后炎症免疫反应是导致心室重构的核心机制。目前,西医通过阻断单个靶点进行抗炎治疗往往收效甚微,而中医气血学说与炎症免疫反应存在相关性,且古代文献及现今临床研究都表明益气活血法对于改善心肌梗死预后有效。故笔者基于气血学说,探讨益气活血法通过调节炎症平衡来改善心梗后心室重构的理论及实践依据,旨在为临床治疗提供一种新思路。

Ventricular remodeling is an important pathophysiological progression of acute myocardial infarction to heart failure,and inflammatory response after myocardial infarction is a"double-edged sword"leading to ventricular remodeling.At present,western medicine often has little effect on anti-inflammatory therapy by blocking a single target,while the theory of qi and blood in traditional Chinese medicine is correlated with inflammatory immune response.Moreover,both ancient literature and current clinical studies show that the method of invigorating qi and activating blood is effective in improving the prognosis of myocardial infarction.Therefore,based on the theory of qi and blood,the author discusses the theoretical and practical basis of improving ventricular remodeling after myocardial infarction by regulating inflammatory balance with the method of invigorating qi and activating blood circulation,in order to provide a new idea for clinical treatment.