缺血性和出血性脑卒中患者血清镁的水平与严重程度、预后及高血压关系

Relationship between Serum Magnesium Levels and Severity,Prognosis and Hypertension in Patients with Ischemic and Hemorrhagic Stroke

目的:镁(Mg)作为神经系统的重要元素,是脑卒中的重要因子。我们旨在确定缺血性和出血型卒中患者的血清Mg水平与患者卒中严重程度、预后及高血压的关系。方法:选取2018年01月~2019年12月本院收治的223例脑卒中患者作为研究对象,根据脑卒中的严重程度及预后根据NIH脑卒中量表(NIHSS)以及入院时血清Mg水平及是否有高血压。通过对比缺血性及出血性脑卒中患者Mg,NIHSS评分及是否高血压,从而得出结论。结果:缺血性患者的Mg水平(1.63±0.42 mg/dl)与出血性脑卒中Mg水平(1.31±0.37 mg/dl)差异具有统计学意义(P≤0.001),且缺血性患者Mg水平与患者预后有关(P<0.001)。高血压(HTN)在缺血性及出血性脑卒中患者之间存在显著差异,同时也作为缺血性及出血性脑卒中患者影响血清Mg的因素之一。结论:缺血性患者中的Mg含量高于出血性脑卒中患者,血清Mg水平与缺血性和出血性脑卒中患者的严重程度无明显相关性。血清Mg水平与缺血性脑卒中患者预后有相关性,但与出血性脑卒中患者预后无明显关系,所以血清Mg水平可作为缺血性卒中预后的预测指标,且Mg含量与导致脑卒中的高血压危险因素有关。

Objective:Magnesium(Mg)as an important element of the nervous system,is an important factor in stroke.We aimed to determine the relationship between serum Mg levels and stroke severity,prognosis,and hypertension in patients with ischemic and hemorrhagic stroke.Methods:From January 2018 to December 2019,The 223 stroke patients admitted in this hospital were used as the research object,according to the severity and prognosis of the stroke according to the NIH Stroke Scale(NIHSS)and the serum Mg level at admission and whether there was hypertension.By comparing Mg,NIHSS scores and hypertension in patients with ischemic and hemorrhagic stroke,the conclusion was drawn.Results:The difference between Mg level in ischemic patients(1.63±0.42 mg/dl)and Mg level in hemorrhagic stroke(1.31±0.37 mg/dl)was statistically significant(P≤0.001).Patient prognosis was related(P<0.001).Hypertension(HTN)has significant differences between patients with ischemic and hemorrhagic stroke,and it is also one of the factors affecting serum Mg in patients with ischemic and hemorrhagic stroke.Conclusion:The content of Mg in ischemic patients is higher than that in patients with hemorrhagic stroke.There is no significant correlation between serum Mg levels and the severity of patients with ischemic and hemorrhagic stroke.Serum Mg level is correlated with the prognosis of patients with ischemic stroke,but it has no significant relationship with the prognosis of patients with hemorrhagic stroke.Therefore,serum Mg level can be used as a predictor of the prognosis of ischemic stroke.Risk factors related to hypertension.