急性心肌梗死合并糖尿病患者冠状动脉介入治疗后心室重构的变化

Changes of Ventricular Remodeling after Coronary Intervention in Patients with Acute Myocardial Infarction and Diabetes Mellitus

目的探讨急性心肌梗死合并糖尿病患者直接经皮冠状动脉介入(PCI)治疗后心室重构的变化。方法选择2017年4月至2019年2月164例急性心肌梗死合并糖尿病患者,对照组82例接受常规药物保守治疗,研究组82例接受PCI治疗。比较两组入院时和PCI后6个月的左心室射血分数(LVEF)、左心室收缩末期容积(LVESV)、舒张末期容积(LVEDV)、左心室质量指数(LVMI)、室壁运动指数(WMI)、球形指数(SI)。结果两组入院时的LVEF、LVESV、LVEDV、LVMI、WMI、SI比较无统计学意义(P>0.05)。研究组PCI后6个月的LVEF、LVESV、LVEDV、LVMI、WMI、SI明显优于对照组,比较具有统计学意义(P<0.05)。结论PCI能够有效改善急性心肌梗死合并糖尿病患者的心室重构。

Objective To investigate the changes of ventricular remodeling after direct percutaneous coronary intervention(PCI)in patients with acute myocardial infarction and diabetes mellitus.Methods 164 cases of patients with acute myocardial infarction complicated with diabetes from April 2017 to February 2019 were selected.The control group with 82 cases received conventional drug conservative treatment,while the study group with 82 cases received PCI.Left ventricular ejection fraction(LVEF),left ventricular end-systolic volume(LVESV),end-diastolic volume(LVEDV),left ventricular mass index(LVMI),ventricular wall motion index(WMI),and spherical index(SI)were compared between the two groups at admission and 6 months after PCI.Results At admission,LVEF,LVESV,LVEDV,LVMI,WMI and SI of the two groups were not statistically signifi cant(P>0.05).LVEF,LVESV,LVEDV,LVMI,WMI and SI of the study group were signifi cantly better than those of the control group at 6 months after PCI,with statistical signifi cance(P<0.05).Conclusion PCI can effectively improve ventricular remodeling in patients with acute myocardial infarction and diabetes mellitus.